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Query: ULK1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ULK1 0 0.633 0.740 -0.520

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ULK1 Phosphorylation S638 -0.154 0.598 _TPS(ph)SQNLLALLAR_
ULK1 Phosphorylation S469 0.035 0.470 _SGSTS(ph)PLGFAR_
ULK1 Phosphorylation T468 -0.247 0.456 _SGST(ph)SPLGFAR_
ULK1 Phosphorylation T636 0.087 _T(ph)PSSQNLLALLAR_
ULK1 Phosphorylation S450 -0.237 -0.173 _NLQS(ph)PTQFQTPR_
ULK1 Phosphorylation T625 -0.547 -0.776 _NPLPPILGSPT(ph)K_
ULK1 Phosphorylation S623 -0.793 -0.874 _NPLPPILGS(ph)PTK_

Background Information for ULK1:


Pubmed-ULK1 »
Uniprot-ULK1 »
Biogrid-ULK1 »
ProteomicsDB-ULK1 »

Tumorportal-ULK1 »
COSMIC-ULK1 »
GenomeRNAi-ULK1 »
Genecards-ULK1


Protein-protein Interactions for ULK1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CCDC53 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ULK1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Ser/Thr_kin_STPK_Ulk-1/2 IPR016237 0.04
Category members Ser/Thr_kinase_C IPR022708 0.04
Category members Kinase-like_dom IPR011009 0.03
Category members Prot_kinase_dom IPR000719 0
Category members Ser-Thr/Tyr_kinase_cat_dom IPR001245 0
Category members Ser/Thr_dual-sp_kinase IPR002290 0
Category members LipoPS_kinase IPR010440 0
Category members RIO-like_kinase IPR018934 0
Category members Tyr_kinase_cat_dom IPR020635 0


Protein complexes (CORUM database) featuring ULK1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ULK1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members Pathway Pathway_724 PID_MTOR_4PATHWAY 0 2
Category members GO Category GO:0004674 protein serine/threonine kinase activity Database 0.66
Category members GO Category GO:0030659 cytoplasmic vesicle membrane Database 0.62
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0008104 protein localization Database 0.5
Category members GO Category GO:0032403 protein complex binding Database 0.49
Category members GO Category GO:0019901 protein kinase binding Database 0.37
Category members GO Category GO:0046777 protein autophosphorylation Database 0.23
Category members GO Category GO:0004672 protein kinase activity Database 0.19
Category members GO Category GO:0007409 axonogenesis Database 0.13
Category members GO Category GO:0031175 neuron projection development Database 0.12
Category members GO Category GO:0003824 catalytic activity Database 0.11
Category members GO Category GO:0016239 positive regulation of macroautophagy Database 0.09
Category members GO Category GO:0043005 neuron projection Database 0.08
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members GO Category GO:0021707 cerebellar granule cell differentiation Database 0.04
Category members GO Category GO:0031102 neuron projection regeneration Database 0.04
Category members GO Category GO:0031623 receptor internalization Database 0.02
Category members GO Category GO:0048675 axon extension Database 0.01
Category members GO Category GO:0004713 protein tyrosine kinase activity Database 0.01
Category members Pathway Pathway_526 KEGG_REGULATION_OF_AUTOPHAGY 0 0
Category members Pathway Pathway_554 KEGG_MTOR_SIGNALING_PATHWAY 0 0
Category members GO Category GO:0000045 autophagic vacuole assembly Database 0
Category members GO Category GO:0000407 pre-autophagosomal structure Database 0
Category members GO Category GO:0005776 autophagic vacuole Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0007265 Ras protein signal transduction Database 0
Category members GO Category GO:0009103 lipopolysaccharide biosynthetic process Database 0
Category members GO Category GO:0010506 regulation of autophagy Database 0
Category members GO Category GO:0010508 positive regulation of autophagy Database 0
Category members GO Category GO:0016772 transferase activity, transferring phosphorus-containing groups Database 0
Category members GO Category GO:0016773 phosphotransferase activity, alcohol group as acceptor Database 0
Category members GO Category GO:0017137 Rab GTPase binding Database 0
Category members GO Category GO:0021933 radial glia guided migration of cerebellar granule cell Database 0
Category members GO Category GO:0031669 cellular response to nutrient levels Database 0
Category members GO Category GO:0034045 pre-autophagosomal structure membrane Database 0
Category members GO Category GO:0042594 response to starvation Database 0
Category members GO Category GO:0043025 neuronal cell body Database 0
Category members GO Category GO:0048671 negative regulation of collateral sprouting Database 0
Category members GO Category GO:0070969 ULK1-ATG13-FIP200 complex Database 0


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