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Query: MCF2L

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MCF2L 1 -1.675 2.560 -1.220

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MCF2L Phosphorylation S100 -0.927 -0.748 _ALEQSQSLPLPAPTSTS(ph)PSR_
MCF2L Phosphorylation S90 -0.968 -0.792 _ALEQSQS(ph)LPLPAPT(ph)STSPSR_

Background Information for MCF2L:


Pubmed-MCF2L »
Uniprot-MCF2L »
Biogrid-MCF2L »
ProteomicsDB-MCF2L »

Tumorportal-MCF2L »
COSMIC-MCF2L »
GenomeRNAi-MCF2L »
Genecards-MCF2L


Protein-protein Interactions for MCF2L
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait MYH9 Cat. description Hein, Mann, Cell 2015


Protein Domains in MCF2L
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Spectrin_repeat IPR002017 2.4
Category members Spectrin/alpha-actinin IPR018159 1.6
Category members PH_domain IPR001849 0.14
Category members SH3_2 IPR011511 0.08
Category members DH-domain IPR000219 0.05
Category members CRAL-TRIO_dom IPR001251 0
Category members SH3_domain IPR001452 0


Protein complexes (CORUM database) featuring MCF2L
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring MCF2L
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0030027 lamellipodium Database 1.77
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0048011 neurotrophin TRK receptor signaling pathway Database 0.63
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0007264 small GTPase mediated signal transduction Database 0.37
Category members GO Category GO:0043065 positive regulation of apoptotic process Database 0.26
Category members GO Category GO:0051056 regulation of small GTPase mediated signal transduction Database 0.25
Category members GO Category GO:0035023 regulation of Rho protein signal transduction Database 0.17
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members Pathway Pathway_1172 PID_RHOA_REG_PATHWAY 0 0.09
Category members GO Category GO:0005089 Rho guanyl-nucleotide exchange factor activity Database 0.08
Category members Pathway Pathway_293 PID_CDC42_REG_PATHWAY 0 0.05
Category members Pathway Pathway_644 PID_TRKR_PATHWAY 0 0.04
Category members GO Category GO:0005545 1-phosphatidylinositol binding Database 0
Category members GO Category GO:0007266 Rho protein signal transduction Database 0
Category members GO Category GO:0035556 intracellular signal transduction Database 0


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