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Query: EHD4

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
EHD4 0 -0.644 0.691 -0.976 -0.173

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
EHD4 Ubiquitylation K165 0.180 -0.366 _SISVIDSPGILSGEK(gl)QR_
EHD4 Ubiquitylation K291 -1.021 _DIQSLPQK(gl)AAVR_

Background Information for EHD4:


Pubmed-EHD4 »
Uniprot-EHD4 »
Biogrid-EHD4 »
ProteomicsDB-EHD4 »

Tumorportal-EHD4 »
COSMIC-EHD4 »
GenomeRNAi-EHD4 »
Genecards-EHD4


Protein-protein Interactions for EHD4
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CLTC Cat. description Hein, Mann, Cell 2015
Category members IP bait C12orf59 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C19orf54 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EXOC8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IQCF1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NTRK3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait OLFM3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PCDHB16 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TNFRSF13B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TPCN2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRIM11 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VWA5A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZFYVE20 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in EHD4
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members Dynamin_GTPase IPR001401 0.36
Category members EPS15_homology IPR000261 0
Category members EF_hand_dom IPR002048 0


Protein complexes (CORUM database) featuring EHD4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring EHD4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members Pathway Pathway_666 KEGG_ENDOCYTOSIS 0 1.25
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members GO Category GO:0031901 early endosome membrane Database 0.58
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members GO Category GO:0005525 GTP binding Database 0.16
Category members GO Category GO:0003924 GTPase activity Database 0.16
Category members GO Category GO:0006907 pinocytosis Database 0.11
Category members GO Category GO:0005509 calcium ion binding Database 0.11
Category members Pathway Pathway_644 PID_TRKR_PATHWAY 0 0.04
Category members Pathway Pathway_1006 PID_MAPK_TRK_PATHWAY 0 0
Category members GO Category GO:0030100 regulation of endocytosis Database 0
Category members GO Category GO:0032456 endocytic recycling Database 0
Category members GO Category GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation Database 0
Category members GO Category GO:0051260 protein homooligomerization Database 0
Category members GO Category GO:0055038 recycling endosome membrane Database 0
Category members GO Category GO:0071363 cellular response to growth factor stimulus Database 0


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