Results for the Category
Early infantile epileptic encephalopathy
(Early_infantile_epileptic_encephalopathy)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| GNAO1 | 1 | 1.200 | -1.320 | 0.217 | -0.334 | -0.374 | ||
| SPTAN1 | 1 | 1.040 | -0.790 | |||||
| SPTAN1 | 1 | 1.040 | -0.790 | -0.323 | -0.738 | 0.512 | 0.509 | |
| CACNA2D2 | 0 | -1.100 | 0.810 | -0.479 | 0.445 | |||
| STXBP1 | 0 | -0.320 | 0.260 | 0.349 | 0.605 | |||
| SLC25A22 | 0 | -0.560 | 0.250 | -1.206 | 0.257 | -0.279 | ||
| PLCB1 | 0 | -0.300 | -0.220 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| GNAO1 | Ubiquitylation | K29 | 0.529 | -0.094 | _NLREDGEK(gl)AAK_ |
| GNAO1 | Ubiquitylation | K92 | 1.569 | _LK(gl)IDFGEAAR_ | |
| GNAO1 | Ubiquitylation | K349 | -0.221 | -0.339 | _NNLK(gl)ECGLY_ |
| PLCB1 | Phosphorylation | S1199 | -0.494 | _TPS(ph)SEELGGDIPGKEFDTPL_ | |
| PLCB1 | Phosphorylation | S1200 | -0.483 | _TPSS(ph)EELGGDIPGKEFDTPL_ | |
| SPTAN1 | Ubiquitylation | K864 | -0.012 | _GNAMVEEGHFAAEDVKAK(gl)_ | |
| SPTAN1 | Phosphorylation | S1029 | 1.169 | 1.417 | _LDPAQS(ph)ASRENLLEEQGSIALR_ |
| SPTAN1 | Phosphorylation | S1031 | 1.169 | 1.397 | _LDPAQSAS(ph)RENLLEEQGSIALR_ |
| SPTAN1 | Ubiquitylation | K1187 | 0.393 | -0.095 | _DETDSK(gl)TASPWK_ |
| SPTAN1 | Ubiquitylation | K1193 | 0.677 | 0.204 | _TASPWK(gl)SAR_ |
| SPTAN1 | Phosphorylation | S1217 | 0.717 | 0.823 | _WRS(ph)LQQLAEER_ |
| SPTAN1 | Ubiquitylation | K2057 | 1.535 | 0.543 | _HVQSK(gl)AIEAR_ |
| STXBP1 | Ubiquitylation | K184 | -0.088 | _LAEQIATLCATLK(gl)EYPAVR_ | |
| STXBP1 | Ubiquitylation | K314 | 1.042 | _SLKDFSSSK(gl)R_ | |
| STXBP1 | Ubiquitylation | K321 | 1.198 | 0.167 | _MNTGEK(gl)TTMR_ |
| STXBP1 | Ubiquitylation | K332 | 0.879 | _DLSQMLK(gl)K_ | |
| STXBP1 | Ubiquitylation | K333 | 0.650 | _DLSQMLKK(gl)_ |
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