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Query: FERMT2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
FERMT2 1 0.876 0.290 -0.340 1.597

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
FERMT2 Phosphorylation S159 -0.331 -0.390 _KLDDQS(ph)EDEALELEGPLITPGSGSIYSSPGLYSK_

Background Information for FERMT2:


Pubmed-FERMT2 »
Uniprot-FERMT2 »
Biogrid-FERMT2 »
ProteomicsDB-FERMT2 »

Tumorportal-FERMT2 »
COSMIC-FERMT2 »
GenomeRNAi-FERMT2 »
Genecards-FERMT2


Protein-protein Interactions for FERMT2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait AP3M1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait F9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FERMT1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FERMT2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FERMT3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RIPPLY2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WDR20 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in FERMT2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Ubiquitin-rel_dom IPR029071 1.79
Category members FERM_N IPR018979 0.36
Category members PH_domain IPR001849 0.14
Category members FERM_domain IPR000299 0
Category members FERM_central IPR019748 0
Category members Band_41_domain IPR019749 0


Protein complexes (CORUM database) featuring FERMT2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring FERMT2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005938 cell cortex Database 2.26
Category members GO Category GO:0030036 actin cytoskeleton organization Database 1.08
Category members GO Category GO:0005925 focal adhesion Database 0.68
Category members GO Category GO:0005856 cytoskeleton Database 0.63
Category members GO Category GO:0034329 cell junction assembly Database 0.29
Category members GO Category GO:0034446 substrate adhesion-dependent cell spreading Database 0.26
Category members Pathway Pathway_560 REACTOME_CELL_CELL_COMMUNICATION 0 0.25
Category members GO Category GO:0007179 transforming growth factor beta receptor signaling pathway Database 0.25
Category members Pathway Pathway_923 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS 0 0.18
Category members GO Category GO:0009986 cell surface Database 0.17
Category members GO Category GO:0031258 lamellipodium membrane Database 0.15
Category members GO Category GO:0016055 Wnt signaling pathway Database 0.11
Category members GO Category GO:0048041 focal adhesion assembly Database 0.1
Category members GO Category GO:0031234 extrinsic to cytoplasmic side of plasma membrane Database 0.1
Category members GO Category GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding Database 0.04
Category members GO Category GO:0001725 stress fiber Database 0.04
Category members GO Category GO:0031941 filamentous actin Database 0.01
Category members Pathway Pathway_925 REACTOME_CELL_JUNCTION_ORGANIZATION 0 0
Category members GO Category GO:0007160 cell-matrix adhesion Database 0
Category members GO Category GO:0007229 integrin-mediated signaling pathway Database 0
Category members GO Category GO:0008360 regulation of cell shape Database 0
Category members GO Category GO:0031674 I band Database 0
Category members GO Category GO:0033622 integrin activation Database 0


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