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Query: DST

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
DST 1 5.213 0.080 -0.480
DST 1 5.213 0.080 -0.480 0.991 1.748
DST 1 5.213 0.080 -0.480 0.796 0.236
DST 1 5.213 0.080 -0.480 0.105 -0.034 0.278

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
DST Phosphorylation S1382 0.207 1.088 _AMVDSQQKS(ph)PVK_
DST Phosphorylation S7512 0.381 _RGS(ph)DASDFDISEIQSVCSDVETVPQTHRPTPR_

Background Information for DST:


Pubmed-DST »
Uniprot-DST »
Biogrid-DST »
ProteomicsDB-DST »

Tumorportal-DST »
COSMIC-DST »
GenomeRNAi-DST »
Genecards-DST


Protein-protein Interactions for DST
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ACTB Cat. description Hein, Mann, Cell 2015
Category members IP bait ADD1 Cat. description Hein, Mann, Cell 2015
Category members IP bait ANLN Cat. description Hein, Mann, Cell 2015
Category members IP bait CALML3 Cat. description Hein, Mann, Cell 2015
Category members IP bait CAPZA2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CEP152 Cat. description Hein, Mann, Cell 2015
Category members IP bait CORO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait DBN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait FLOT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait IQGAP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait LIMA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MAPRE1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH9 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO18A Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP1CB Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP6C Cat. description Hein, Mann, Cell 2015
Category members IP bait PRKCZ Cat. description Hein, Mann, Cell 2015
Category members IP bait TECPR2 Cat. description Hein, Mann, Cell 2015
Category members IP bait TPM1 Cat. description Hein, Mann, Cell 2015
Category members IP bait COPS7B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MAGEA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MAPRE1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in DST
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Spectrin_repeat IPR002017 2.4
Category members Spectrin/alpha-actinin IPR018159 1.6
Category members CH-domain IPR001715 0.63
Category members ABC1_TM_dom IPR011527 0.33
Category members CAMSAP_CH IPR022613 0.13
Category members Plectin_repeat IPR001101 0.1
Category members EF_hand_dom IPR002048 0
Category members GAS2_dom IPR003108 0


Protein complexes (CORUM database) featuring DST
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring DST
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005635 nuclear envelope Database 7.22
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0003779 actin binding Database 5.41
Category members GO Category GO:0031252 cell leading edge Database 2.52
Category members GO Category GO:0005938 cell cortex Database 2.26
Category members GO Category GO:0015629 actin cytoskeleton Database 2.22
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members GO Category GO:0008022 protein C-terminus binding Database 1.43
Category members GO Category GO:0015630 microtubule cytoskeleton Database 1.34
Category members GO Category GO:0008017 microtubule binding Database 0.79
Category members GO Category GO:0005856 cytoskeleton Database 0.63
Category members Pathway Pathway_208 PID_TAP63_PATHWAY 0 0.52
Category members GO Category GO:0000226 microtubule cytoskeleton organization Database 0.5
Category members GO Category GO:0051010 microtubule plus-end binding Database 0.47
Category members GO Category GO:0030011 maintenance of cell polarity Database 0.35
Category members GO Category GO:0031110 regulation of microtubule polymerization or depolymerization Database 0.35
Category members GO Category GO:0031673 H zone Database 0.32
Category members GO Category GO:0030018 Z disc Database 0.32
Category members GO Category GO:0030198 extracellular matrix organization Database 0.26
Category members GO Category GO:0045111 intermediate filament cytoskeleton Database 0.26
Category members GO Category GO:0030424 axon Database 0.23
Category members GO Category GO:0016023 cytoplasmic membrane-bounded vesicle Database 0.17
Category members GO Category GO:0007409 axonogenesis Database 0.13
Category members GO Category GO:0055085 transmembrane transport Database 0.12
Category members GO Category GO:0005509 calcium ion binding Database 0.11
Category members GO Category GO:0030056 hemidesmosome Database 0.1
Category members GO Category GO:0005178 integrin binding Database 0.09
Category members GO Category GO:0042626 ATPase activity, coupled to transmembrane movement of substances Database 0.09
Category members GO Category GO:0008090 retrograde axon cargo transport Database 0.08
Category members Disease phenotype Autosomal_recessive_epidermolysis_bullosa_simplex Autosomal recessive epidermolysis bullosa simplex Database 0
Category members GO Category GO:0005604 basement membrane Database 0
Category members GO Category GO:0005882 intermediate filament Database 0
Category members GO Category GO:0006810 transport Database 0
Category members GO Category GO:0007010 cytoskeleton organization Database 0
Category members GO Category GO:0007050 cell cycle arrest Database 0
Category members GO Category GO:0007155 cell adhesion Database 0
Category members GO Category GO:0007229 integrin-mediated signaling pathway Database 0
Category members GO Category GO:0009405 pathogenesis Database 0
Category members GO Category GO:0009611 response to wounding Database 0
Category members GO Category GO:0009925 basal plasma membrane Database 0
Category members GO Category GO:0031122 cytoplasmic microtubule organization Database 0
Category members GO Category GO:0031581 hemidesmosome assembly Database 0
Category members GO Category GO:0035371 microtubule plus-end Database 0
Category members GO Category GO:0042803 protein homodimerization activity Database 0
Category members GO Category GO:0045104 intermediate filament cytoskeleton organization Database 0
Category members GO Category GO:0048870 cell motility Database 0
Category members GO Category GO:0060053 neurofilament cytoskeleton Database 0


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