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bioLOGIC Data

Query: TAOK3

RNAi screen result	RNAPII IP (PI)	CSB IP	CSB IP (PI)	Chrom.	Chrom. (PI)	Phosphorylation	Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:
Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen

Gene name	Point score	Z-score sums	RNAi high	RNAi low	RNAPII-IP (PI)	CSB-IP	CSB-IP (PI)	Chrom.	Chrom. (PI)
TAOK3	0	2.587	-0.440	0.370
TAOK3	0	2.587	-0.440	0.370					1.169

PTM Sites:
Back to Protein Results | Red/green: hit at lower/upper end of the respective screen

Gene name	PTM type	PTM site	UV	UV (PI)	Sequence
TAOK3	Phosphorylation	S324	0.159	0.189	_NGPLNES(ph)QEDEEDSEHGTSLNR_
TAOK3	Phosphorylation	S9	-0.793	0.108	_AGS(ph)LKDPEIAELFFKEDPEK_
TAOK3	Phosphorylation	S421	-0.535	-0.355	_ASDPQS(ph)PPQVSR_
TAOK3	Ubiquitylation	K587	0.700		_QEWLSK(gl)QK_

Background Information for TAOK3:

Pubmed-TAOK3 »

Uniprot-TAOK3 »

Biogrid-TAOK3 »

ProteomicsDB-TAOK3 »

Tumorportal-TAOK3 »

COSMIC-TAOK3 »

GenomeRNAi-TAOK3 »

Genecards-TAOK3

Protein-protein Interactions for TAOK3

Show screen data for	Category Name and Description	Link to cat description	Data Source
Category members	IP bait CTR9	Cat. description	Hein, Mann, Cell 2015

Protein Domains in TAOK3

	Domain name	Domain Description	TC-NER relevance -log10(p-value)
Category members	Kinase-like_dom	IPR011009	0.03
Category members	Prot_kinase_dom	IPR000719	0
Category members	Ser-Thr/Tyr_kinase_cat_dom	IPR001245	0
Category members	Ser/Thr_dual-sp_kinase	IPR002290	0
Category members	Aminoglycoside_PTrfase	IPR002575	0
Category members	Tyr_kinase_cat_dom	IPR020635	0

Protein complexes (CORUM database) featuring TAOK3

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)

Categories featuring TAOK3

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)
Category members	GO Category	GO:0005515	protein binding	Database	INF
Category members	GO Category	GO:0006281	DNA repair	Database	INF
Category members	GO Category	GO:0005524	ATP binding	Database	5.54
Category members	GO Category	GO:0006974	cellular response to DNA damage stimulus	Database	3.57
Category members	GO Category	GO:0005739	mitochondrion	Database	1.67
Category members	GO Category	GO:0005886	plasma membrane	Database	1.21
Category members	GO Category	GO:0004674	protein serine/threonine kinase activity	Database	0.66
Category members	GO Category	GO:0046777	protein autophosphorylation	Database	0.23
Category members	GO Category	GO:0016301	kinase activity	Database	0.23
Category members	GO Category	GO:0004672	protein kinase activity	Database	0.19
Category members	GO Category	GO:0004709	MAP kinase kinase kinase activity	Database	0.08
Category members	GO Category	GO:0016740	transferase activity	Database	0.07
Category members	GO Category	GO:0006468	protein phosphorylation	Database	0.04
Category members	GO Category	GO:0004860	protein kinase inhibitor activity	Database	0.03
Category members	GO Category	GO:0004713	protein tyrosine kinase activity	Database	0.01
Category members	Pathway	Pathway_1098	PID_P38_MKK3_6PATHWAY	0	0
Category members	Pathway	Pathway_715	KEGG_MAPK_SIGNALING_PATHWAY	0	0
Category members	GO Category	GO:0000165	MAPK cascade	Database	0
Category members	GO Category	GO:0006469	negative regulation of protein kinase activity	Database	0
Category members	GO Category	GO:0016772	transferase activity, transferring phosphorus-containing groups	Database	0
Category members	GO Category	GO:0031572	G2 DNA damage checkpoint	Database	0
Category members	GO Category	GO:0032874	positive regulation of stress-activated MAPK cascade	Database	0
Category members	GO Category	GO:0043507	positive regulation of JUN kinase activity	Database	0
Category members	GO Category	GO:0046329	negative regulation of JNK cascade	Database	0
Category members	GO Category	GO:0046330	positive regulation of JNK cascade	Database	0