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negative regulation of JNK cascade
(GO:0046329)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
PAFAH1B1 1 0.820 -0.330 1.632 0.711
ITCH 1 1.000 -0.610 -0.346 0.023 0.613
MECOM 0 0.130 -0.120 -0.189 0.565 -1.171
MECOM 0 0.740 -0.750 -0.189 0.565 -1.171
DUSP3 0 0.360 -0.500
MEN1 0 1.080 -1.150 0.101 0.684 -0.063
MEN1 0 1.080 -1.150 0.395
MEN1 0 1.080 -1.150
TAOK3 0 -0.440 0.370
TAOK3 0 -0.440 0.370 1.169
NCOR1 0 -0.820 1.130 -0.827 -0.215 0.037
AKT1 0 -0.050 0.700
AKT1 0 0.860 -0.040
F2RL1 0 -1.330 2.490
HDAC3 0 -0.790 1.070

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
AKT1 Phosphorylation S124 0.252 0.311 _SGS(ph)PSDNSGAEEMEVSLAKPK_
AKT1 Phosphorylation S126 -0.241 _SGSPS(ph)DNSGAEEM(ox)EVSLAK_
AKT1 Ubiquitylation K301 0.988 _EGIK(gl)DGATMK_
DUSP3 Ubiquitylation K116 -0.586 _AADFIDQALAQK(gl)NGR_
F2RL1 Ubiquitylation K368 0.159 0.737 _TVK(gl)QMQVSLTSK_
F2RL1 Ubiquitylation K377 -0.040 -0.268 _QMQVSLTSK(gl)K_
F2RL1 Ubiquitylation K378 0.066 -0.268 _QMQVSLTSKK(gl)_
F2RL1 Phosphorylation S384 0.573 1.068 _KSS(ph)SYSSSSTTVK_
F2RL1 Ubiquitylation K394 0.350 0.873 _KSSSYSSSSTTVK(gl)TSY_
HDAC3 Phosphorylation S424 -0.354 _GPEENYSRPEAPNEFYDGDHDNDKES(ph)DVEI_
ITCH Ubiquitylation K66 -0.890 _WK(gl)QPLTVIVTPVSK_
ITCH Ubiquitylation K350 0.049 0.396 _VYYVDHVEK(gl)R_
ITCH Ubiquitylation K446 -1.514 -1.539 _EFDPLGPLPPGWEK(gl)R_
ITCH Ubiquitylation K478 -1.265 _SQGQLNEK(gl)PLPEGWEMR_
ITCH Ubiquitylation K513 -0.564 1.593 _TGK(gl)SALDNGPQIAYVR_
ITCH Ubiquitylation K861 -0.810 0.596 _VGK(gl)ENWLPR_
MECOM Phosphorylation S62 -1.041 -0.744 _EGS(ph)PYKAPIYIPDDIPIPAEFELR_
MECOM Phosphorylation S1039 -0.074 0.136 _NFIGNSNHGSQS(ph)PR_
MEN1 Ubiquitylation K8 -1.132 0.088 _AAQK(gl)TLFPLR_
MEN1 Phosphorylation S218 -0.820 _RES(ph)KPEEPPPPK_
NCOR1 Phosphorylation S1195 -0.029 0.716 _MPIEDS(ph)SPEKGREEAASK_
NCOR1 Phosphorylation S1196 0.087 0.141 _MPIEDSS(ph)PEKGR_
NCOR1 Phosphorylation S1472 0.700 0.536 _AQLS(ph)PGIYDDTSAR_
NCOR1 Phosphorylation S1977 -0.959 -0.974 _YETPSDAIEVIS(ph)PASSPAPPQEK_
NCOR1 Ubiquitylation K1998 -2.086 _LQTYQPEVVK(gl)ANQAENDPTR_
NCOR1 Phosphorylation S2120 0.148 0.154 _VS(ph)PENLVDK_
NCOR1 Phosphorylation S2151 -1.006 -0.922 _SHVSSEPYEPIS(ph)PPQVPVVHEK_
NCOR1 Phosphorylation S2184 0.120 0.226 _S(ph)PGSISYLPSFFTK_
NCOR1 Phosphorylation S2187 0.396 _SPGS(ph)ISYLPSFFTK_
PAFAH1B1 Ubiquitylation K76 -0.530 _LNEAK(gl)EEFTSGGPLGQK_
TAOK3 Phosphorylation S9 -0.793 0.108 _AGS(ph)LKDPEIAELFFKEDPEK_
TAOK3 Phosphorylation S324 0.159 0.189 _NGPLNES(ph)QEDEEDSEHGTSLNR_
TAOK3 Phosphorylation S421 -0.535 -0.355 _ASDPQS(ph)PPQVSR_
TAOK3 Ubiquitylation K587 0.700 _QEWLSK(gl)QK_


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