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Query: TPD52L1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TPD52L1 0 2.320 -1.170 1.190

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TPD52L1 Phosphorylation S149 0.484 0.646 _NSPTFKS(ph)FEER_
TPD52L1 Phosphorylation T146 0.503 _NSPT(ph)FKSFEER_

Background Information for TPD52L1:


Pubmed-TPD52L1 »
Uniprot-TPD52L1 »
Biogrid-TPD52L1 »
ProteomicsDB-TPD52L1 »

Tumorportal-TPD52L1 »
COSMIC-TPD52L1 »
GenomeRNAi-TPD52L1 »
Genecards-TPD52L1


Protein-protein Interactions for TPD52L1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ADC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PSMC3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TPD52L2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TPD52L1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members TPD52 IPR007327 0.47


Protein complexes (CORUM database) featuring TPD52L1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring TPD52L1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_474 REACTOME_MEMBRANE_TRAFFICKING 0 1.14
Category members Pathway Pathway_475 REACTOME_TRANS_GOLGI_NETWORK_VESICLE_BUDDING 0 0.98
Category members Pathway Pathway_520 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS 0 0.78
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members GO Category GO:0000086 G2/M transition of mitotic cell cycle Database 0.33
Category members GO Category GO:0046982 protein heterodimerization activity Database 0.28
Category members GO Category GO:0006309 apoptotic DNA fragmentation Database 0.26
Category members GO Category GO:0042802 identical protein binding Database 0.26
Category members GO Category GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process Database 0.08
Category members GO Category GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process Database 0
Category members GO Category GO:0042803 protein homodimerization activity Database 0
Category members GO Category GO:0043406 positive regulation of MAP kinase activity Database 0
Category members GO Category GO:0046330 positive regulation of JNK cascade Database 0


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