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positive regulation of MAP kinase activity
(GO:0043406)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
TAB1 1 1.890 -0.670
TAB1 1 1.890 -0.670 1.657
KRAS 1 -0.510 0.620 1.031 0.887
KRAS 1 -0.510 0.620 0.246 -0.346
ILK 1 -1.560 3.680 -0.463 -0.527
PDGFA 1 0.190 -0.340 -2.109 1.885
FGFR1 0 0.210 0.150
PSEN1 0 0.930 -1.110
FLT1 0 -1.240 1.900
CSK 0 1.200 -0.960 -1.211
CSK 0 1.200 -0.960
TGFB1 0 -0.550 1.050
EZH2 0 1.100 -0.960 0.524 0.464 -0.045
TPD52L1 0 -1.170 1.190
PDCD10 0 0.750 -0.920 0.405
AJUBA 0 -0.310 0.400
PDE5A 0 0.210 0.250
ERBB2 0 -1.310 1.360
EGFR 0 -0.580 0.520 0.513 0.090
PRKCD 0 0.250 0.070 0.578 0.427
HRAS 0 1.470 -0.520
MIF 0 1.480 -0.910 -0.887 -0.872 -1.709 0.653

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
AJUBA Phosphorylation S119 0.930 _LEPTAPALS(ph)PR_
CSK Ubiquitylation K196 -0.133 _SGWALNMKELK(gl)_
EGFR Phosphorylation T693 0.486 -0.139 _ELVEPLT(ph)PSGEAPNQALLR_
EGFR Phosphorylation S991 -0.041 _MHLPS(ph)PTDSNFYR_
ERBB2 Ubiquitylation K200 -2.073 _ACHPCSPMCK(gl)GSR_
ERBB2 Ubiquitylation K369 -0.742 _AVTSANIQEFAGCKK(gl)_
ERBB2 Ubiquitylation K747 -0.505 -0.019 _GIWIPDGENVK(gl)IPVAIK_
ERBB2 Ubiquitylation K854 -0.859 _NVLVK(gl)SPNHVK_
ERBB2 Phosphorylation S1054 -0.476 -0.706 _S(ph)GGGDLTLGLEPSEEEAPR_
EZH2 Ubiquitylation K61 0.548 _TEILNQEWK(gl)QR_
EZH2 Phosphorylation S363 0.010 -0.733 _GRLPNNSS(ph)RPSTPTINVLESK_
EZH2 Phosphorylation S366 -0.266 -0.699 _GRLPNNSSRPS(ph)TPTINVLESK_
EZH2 Phosphorylation T367 0.320 -0.372 _LPNNSSRPST(ph)PTINVLESK_
EZH2 Phosphorylation T369 -0.911 _GRLPNNSSRPSTPT(ph)INVLESK_
EZH2 Phosphorylation T487 -0.501 -0.532 _VKESSIIAPAPAEDVDT(ph)PPR_
EZH2 Ubiquitylation K569 -0.974 _AQCNTK(gl)QCPCYLAVR_
EZH2 Ubiquitylation K713 -0.461 _IGIFAK(gl)R_
EZH2 Ubiquitylation K735 0.038 _YSQADALK(gl)YVGIER_
FGFR1 Ubiquitylation K510 1.047 -0.221 _VTK(gl)VAVK_
FLT1 Ubiquitylation K953 -1.081 _MEPGLEQGK(gl)KPR_
HRAS Ubiquitylation K170 -1.005 _K(gl)LNPPDESGPGCMSCK_
ILK Ubiquitylation K85 -0.777 _DIVQK(gl)LLQYK_
ILK Ubiquitylation K426 -0.300 _LMK(gl)ICMNEDPAK_
ILK Ubiquitylation K435 -2.732 _ICMNEDPAK(gl)RPK_
KRAS Ubiquitylation K128 1.528 1.433 _TVDTK(gl)QAHELAK_
KRAS Ubiquitylation K235 0.591 0.087 _TVDTK(gl)QAQDLAR_
KRAS Ubiquitylation K254 -0.450 -0.156 _SYGIPFIETSAK(gl)TR_
MIF Ubiquitylation K78 0.018 0.329 _SYSK(gl)LLCGLLAER_
PDCD10 Ubiquitylation K183 -0.107 _TYFK(gl)DGK_
PDE5A Phosphorylation S86 0.392 0.402 _GHTESCSCPLQQS(ph)PR_
PRKCD Ubiquitylation K138 -0.141 _SEDEAK(gl)FPTMNR_
PRKCD Ubiquitylation K222 0.185 0.658 _DTIFQK(gl)ER_
PRKCD Phosphorylation S302 -0.240 -0.222 _S(ph)DSASSEPVGIYQGFEK_
PRKCD Phosphorylation S304 0.378 0.289 _RSDS(ph)ASSEPVGIYQGFEK_
PRKCD Phosphorylation S506 -0.213 0.200 _AS(ph)TFCGTPDYIAPEILQGLK_
PRKCD Phosphorylation T507 -0.149 0.240 _AS(ph)TFCGTPDYIAPEILQGLK_
PRKCD Ubiquitylation K641 -2.000 _DYSNFDQEFLNEK(gl)AR_
PRKCD Phosphorylation S645 0.577 0.832 _ARLS(ph)YSDK_
PRKCD Phosphorylation S647 0.886 0.853 _ARLSYS(ph)DK_
PSEN1 Phosphorylation S313 0.844 _VSKNS(ph)KYNAESTER_
PSEN1 Ubiquitylation K314 0.016 0.414 _NSK(gl)YNAESTER_
PSEN1 Phosphorylation S366 -0.340 0.055 _AAVQELSS(ph)SILAGEDPEER_
PSEN1 Phosphorylation S367 0.005 0.066 _AAVQELSSS(ph)ILAGEDPEER_
TAB1 Phosphorylation S7 -0.170 0.140 _S(ph)LLQSEQQPSWTDDLPLCHLSGVGSASNR_
TAB1 Phosphorylation S16 -0.138 0.069 _SLLQSEQQPS(ph)WTDDLPLCHLSGVGSASNR_
TAB1 Ubiquitylation K186 -1.015 _SYSADGK(gl)GTESHPPEDSWLK_
TAB1 Ubiquitylation K371 0.032 _LSQLGLDAGK(gl)IK_
TAB1 Ubiquitylation K373 -0.007 _LSQLGLDAGKIK(gl)_
TGFB1 Ubiquitylation K50 -0.557 _GQILSK(gl)LR_
TPD52L1 Phosphorylation T146 0.503 _NSPT(ph)FKSFEER_
TPD52L1 Phosphorylation S149 0.484 0.646 _NSPTFKS(ph)FEER_


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