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Query: AJUBA

This is a cancer-associated gene according to the Broad cancer gene census.

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
AJUBA 0 1.330 -0.310 0.400

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
AJUBA Phosphorylation S119 0.930 _LEPTAPALS(ph)PR_

Background Information for AJUBA:


Pubmed-AJUBA »
Uniprot-AJUBA »
Biogrid-AJUBA »
ProteomicsDB-AJUBA »

Tumorportal-AJUBA »
COSMIC-AJUBA »
GenomeRNAi-AJUBA »
Genecards-AJUBA


Protein-protein Interactions for AJUBA
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in AJUBA
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Znf_LIM IPR001781 0


Protein complexes (CORUM database) featuring AJUBA
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring AJUBA
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0003682 chromatin binding Database 6.07
Category members GO Category GO:0030027 lamellipodium Database 1.77
Category members GO Category GO:0005911 cell-cell junction Database 1.4
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members Human mutations Broad_cancer_genes Broad cancer genes (Lawrence et al., 2014) literature 1.14
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0051015 actin filament binding Database 0.99
Category members GO Category GO:0031334 positive regulation of protein complex assembly Database 0.69
Category members GO Category GO:0007049 cell cycle Database 0.69
Category members GO Category GO:0005925 focal adhesion Database 0.68
Category members GO Category GO:0030032 lamellipodium assembly Database 0.66
Category members GO Category GO:0030334 regulation of cell migration Database 0.61
Category members GO Category GO:0005815 microtubule organizing center Database 0.39
Category members GO Category GO:0033674 positive regulation of kinase activity Database 0.3
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0005667 transcription factor complex Database 0.19
Category members GO Category GO:0048041 focal adhesion assembly Database 0.1
Category members GO Category GO:0000932 cytoplasmic mRNA processing body Database 0.08
Category members GO Category GO:0033673 negative regulation of kinase activity Database 0.07
Category members GO Category GO:0034613 cellular protein localization Database 0.04
Category members GO Category GO:0035195 gene silencing by miRNA Database 0.04
Category members GO Category GO:0045294 alpha-catenin binding Database 0.03
Category members GO Category GO:0000122 negative regulation of transcription from RNA polymerase II promoter Database 0.02
Category members GO Category GO:0001666 response to hypoxia Database 0
Category members GO Category GO:0003714 transcription corepressor activity Database 0
Category members GO Category GO:0016339 calcium-dependent cell-cell adhesion Database 0
Category members GO Category GO:0035313 wound healing, spreading of epidermal cells Database 0
Category members GO Category GO:0035331 negative regulation of hippo signaling Database 0
Category members GO Category GO:0043087 regulation of GTPase activity Database 0
Category members GO Category GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling Database 0
Category members GO Category GO:0043406 positive regulation of MAP kinase activity Database 0
Category members GO Category GO:0046474 glycerophospholipid biosynthetic process Database 0


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