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Query: FZD7

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
FZD7 1 0.869 2.260 -1.160

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
FZD7 Ubiquitylation K569 0.551 0.319 _LSHSSK(gl)GETAV_

Background Information for FZD7:


Pubmed-FZD7 »
Uniprot-FZD7 »
Biogrid-FZD7 »
ProteomicsDB-FZD7 »

Tumorportal-FZD7 »
COSMIC-FZD7 »
GenomeRNAi-FZD7 »
Genecards-FZD7


Protein-protein Interactions for FZD7
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ATP2B2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LAMP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC39A4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait UPK1A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VNN2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZACN Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in FZD7
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members GPCR_2-like IPR017981 0.05
Category members Frizzled IPR000539 0.03
Category members Frizzled_dom IPR020067 0


Protein complexes (CORUM database) featuring FZD7
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring FZD7
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members Pathway Pathway_1105 REACTOME_GPCR_LIGAND_BINDING 0 2.35
Category members GO Category GO:0004930 G-protein coupled receptor activity Database 2.1
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members Pathway Pathway_1104 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS 0 0.93
Category members Pathway Pathway_256 REACTOME_SIGNALING_BY_GPCR 0 0.83
Category members GO Category GO:0042327 positive regulation of phosphorylation Database 0.52
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0019827 stem cell maintenance Database 0.48
Category members GO Category GO:0010812 negative regulation of cell-substrate adhesion Database 0.47
Category members GO Category GO:0030165 PDZ domain binding Database 0.29
Category members Pathway Pathway_1093 PID_SYNDECAN_4_PATHWAY 0 0.28
Category members GO Category GO:0045893 positive regulation of transcription, DNA-dependent Database 0.28
Category members GO Category GO:0034446 substrate adhesion-dependent cell spreading Database 0.26
Category members GO Category GO:0001944 vasculature development Database 0.24
Category members GO Category GO:0004888 transmembrane signaling receptor activity Database 0.15
Category members GO Category GO:0007409 axonogenesis Database 0.13
Category members GO Category GO:0007166 cell surface receptor signaling pathway Database 0.1
Category members Pathway Pathway_679 KEGG_WNT_SIGNALING_PATHWAY 0 0.09
Category members Pathway Pathway_417 PID_WNT_NONCANONICAL_PATHWAY 0 0.09
Category members GO Category GO:0008406 gonad development Database 0.06
Category members GO Category GO:0035412 regulation of catenin import into nucleus Database 0.04
Category members GO Category GO:0033077 T cell differentiation in thymus Database 0.03
Category members GO Category GO:0017147 Wnt-protein binding Database 0.02
Category members Pathway Pathway_1163 KEGG_BASAL_CELL_CARCINOMA 0 0
Category members Pathway Pathway_1277 PID_WNT_SIGNALING_PATHWAY 0 0
Category members Pathway Pathway_24 KEGG_PATHWAYS_IN_CANCER 0 0
Category members Pathway Pathway_244 KEGG_MELANOGENESIS 0 0
Category members Pathway Pathway_290 WNT_SIGNALING 0 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0007199 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger Database 0
Category members GO Category GO:0007223 Wnt signaling pathway, calcium modulating pathway Database 0
Category members GO Category GO:0007420 brain development Database 0
Category members GO Category GO:0014834 satellite cell maintenance involved in skeletal muscle regeneration Database 0
Category members GO Category GO:0030182 neuron differentiation Database 0
Category members GO Category GO:0032589 neuron projection membrane Database 0
Category members GO Category GO:0035567 non-canonical Wnt signaling pathway Database 0
Category members GO Category GO:0038031 non-canonical Wnt signaling pathway via JNK cascade Database 0
Category members GO Category GO:0042813 Wnt-activated receptor activity Database 0
Category members GO Category GO:0045177 apical part of cell Database 0
Category members GO Category GO:0046330 positive regulation of JNK cascade Database 0
Category members GO Category GO:0048103 somatic stem cell division Database 0
Category members GO Category GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing Database 0
Category members GO Category GO:0060070 canonical Wnt signaling pathway Database 0
Category members GO Category GO:0060231 mesenchymal to epithelial transition Database 0
Category members GO Category GO:0071300 cellular response to retinoic acid Database 0


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