bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Category

Results for the Category
KEGG_BASAL_CELL_CARCINOMA
(Pathway_1163)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
GSK3B 2 1.020 -0.870 -1.128 1.091
SMO 1 -0.690 1.110 1.532
TCF7L1 1 -2.040 2.970 -0.741
FZD7 1 2.260 -1.160
DVL2 0 -0.050 0.580
TCF7 0 1.040 -0.330 -0.741
GLI3 0 -0.980 1.650
SUFU 0 1.190 -0.990
WNT5A 0
APC 0 0.810 -0.720 0.008 0.065
APC2 0 0.850 -0.820 0.008 0.065
LEF1 0 -0.710 0.790 -0.741
TP53 0 -1.070 1.050 -2.808 0.076 -0.094 0.436 0.497
TCF7L2 0 -0.550 0.790 -0.741
DVL3 0 0.890 -0.290
FZD5 0 -0.880 0.520
CTNNB1 0 0.490 -0.230
CTNNB1 0 0.490 -0.230 -0.415 0.628 0.215
PTCH1 0 0.630 -0.690

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
APC Phosphorylation S746 0.284 0.140 _DANIMS(ph)PGSSLPSLHVR_
APC Phosphorylation S749 0.276 _YKDANIM(ox)SPGS(ph)SLPSLHVR_
APC Phosphorylation S782 -0.471 -0.446 _ALEAELDAQHLSETFDNIDNLS(ph)PK_
APC Phosphorylation S1044 0.097 0.452 _YSDEQLNSGRQS(ph)PSQNER_
APC Phosphorylation S1046 0.412 1.084 _YSDEQLNSGRQSPS(ph)QNER_
APC Phosphorylation S1362 -0.007 0.328 _AVEFSSGAKS(ph)PSK_
APC Phosphorylation T1440 -1.261 -0.875 _SKT(ph)PPPPPQTAQTK_
APC Phosphorylation T1775 0.099 _KPT(ph)SPVKPIPQNTEYR_
APC Phosphorylation S1776 0.019 0.099 _KPTS(ph)PVKPIPQNTEYR_
APC Phosphorylation S2095 0.363 _DIQRPDSEHGLS(ph)PDSENFDWK_
APC Phosphorylation S2127 -0.031 _AIQEGANSIVSSLHQAAAAACLS(ph)R_
APC Phosphorylation S2260 -0.624 _TPAS(ph)KSPSEGQTATTSPR_
APC Phosphorylation S2262 -0.026 0.240 _TPASKS(ph)PSEGQTATTSPR_
APC Phosphorylation S2451 -0.249 -0.285 _EAPS(ph)PTLR_
APC Phosphorylation S2537 -0.505 _SHSES(ph)PSRLPINR_
APC Phosphorylation S2571 0.693 0.817 _TGS(ph)SSSILSASSESSEK_
APC Phosphorylation S2673 0.326 0.501 _S(ph)GRSPTGNTPPVIDSVSEK_
APC Phosphorylation S2676 -0.478 0.096 _SGRS(ph)PTGNTPPVIDSVSEK_
APC Phosphorylation T2678 -0.028 0.136 _SPT(ph)GNTPPVIDSVSEK_
APC2 Phosphorylation S746 0.284 0.140 _DANIMS(ph)PGSSLPSLHVR_
APC2 Phosphorylation S749 0.276 _YKDANIM(ox)SPGS(ph)SLPSLHVR_
APC2 Phosphorylation S782 -0.471 -0.446 _ALEAELDAQHLSETFDNIDNLS(ph)PK_
APC2 Phosphorylation S1044 0.097 0.452 _YSDEQLNSGRQS(ph)PSQNER_
APC2 Phosphorylation S1046 0.412 1.084 _YSDEQLNSGRQSPS(ph)QNER_
APC2 Phosphorylation S1362 -0.007 0.328 _AVEFSSGAKS(ph)PSK_
APC2 Phosphorylation T1440 -1.261 -0.875 _SKT(ph)PPPPPQTAQTK_
APC2 Phosphorylation T1775 0.099 _KPT(ph)SPVKPIPQNTEYR_
APC2 Phosphorylation S1776 0.019 0.099 _KPTS(ph)PVKPIPQNTEYR_
APC2 Phosphorylation S2095 0.363 _DIQRPDSEHGLS(ph)PDSENFDWK_
APC2 Phosphorylation S2127 -0.031 _AIQEGANSIVSSLHQAAAAACLS(ph)R_
APC2 Phosphorylation S2260 -0.624 _TPAS(ph)KSPSEGQTATTSPR_
APC2 Phosphorylation S2262 -0.026 0.240 _TPASKS(ph)PSEGQTATTSPR_
APC2 Phosphorylation S2451 -0.249 -0.285 _EAPS(ph)PTLR_
APC2 Phosphorylation S2537 -0.505 _SHSES(ph)PSRLPINR_
APC2 Phosphorylation S2571 0.693 0.817 _TGS(ph)SSSILSASSESSEK_
APC2 Phosphorylation S2673 0.326 0.501 _S(ph)GRSPTGNTPPVIDSVSEK_
APC2 Phosphorylation S2676 -0.478 0.096 _SGRS(ph)PTGNTPPVIDSVSEK_
APC2 Phosphorylation T2678 -0.028 0.136 _SPT(ph)GNTPPVIDSVSEK_
CTNNB1 Ubiquitylation K158 -1.265 _AIPELTK(gl)LLNDEDQVVVNK_
CTNNB1 Ubiquitylation K180 -0.546 -0.636 _AAVM(ox)VHQLSK(gl)K_
CTNNB1 Ubiquitylation K181 -0.717 -0.729 _AAVMVHQLSKK(gl)_
CTNNB1 Phosphorylation S191 -0.024 0.129 _S(ph)PQMVSAIVR_
CTNNB1 Ubiquitylation K435 -0.350 _NK(gl)MM(ox)VCQVGGIEALVR_
CTNNB1 Ubiquitylation K496 -1.262 _LHYGLPVVVK(gl)_
CTNNB1 Phosphorylation S552 1.233 1.224 _RTS(ph)MGGTQQQFVEGVR_
CTNNB1 Phosphorylation T556 1.275 0.995 _RTSM(ox)GGT(ph)QQQFVEGVR_
CTNNB1 Ubiquitylation K671 -0.941 -0.934 _MSEDKPQDYK(gl)K_
DVL2 Ubiquitylation K343 0.846 -1.366 _DIVHK(gl)PGPIVLTVAK_
DVL3 Phosphorylation S112 -0.787 _TGGIGDS(ph)RPPSFHPHAGGGSQENLDNDTETDSLVSAQR_
DVL3 Phosphorylation S125 -0.854 -0.531 _TGGIGDSRPPSFHPHAGGGS(ph)QENLDNDTETDSLVSAQR_
FZD5 Ubiquitylation K209 -0.563 _ESHPLYNK(gl)VR_
FZD7 Ubiquitylation K569 0.551 0.319 _LSHSSK(gl)GETAV_
GLI3 Phosphorylation S664 -0.582 -0.252 _S(ph)PGRPTQGALGEQQDLSNTTSK_
GSK3B Phosphorylation S9 -0.483 0.010 _TTS(ph)FAESCKPVQQPSAFGSMK_
GSK3B Ubiquitylation K85 -0.204 _LCDSGELVAIK(gl)K_
GSK3B Ubiquitylation K86 -0.204 _LCDSGELVAIK(gl)K_
GSK3B Phosphorylation S215 0.296 0.477 _GEPNVS(ph)YICSR_
GSK3B Phosphorylation Y216 0.356 0.376 _GEPNVSY(ph)ICSR_
GSK3B Phosphorylation T390 2.800 2.527 _IQAAAST(ph)PTNATAASDANTGDR_
LEF1 Ubiquitylation K88 -0.867 -0.222 _ESLEEAAK(gl)R_
PTCH1 Ubiquitylation K904 -0.390 _DKPIDISQLTK(gl)QR_
SUFU Ubiquitylation K303 -0.015 _RLSGK(gl)DTEQIR_
SUFU Ubiquitylation K321 -1.917 -1.398 _GLEINSK(gl)PVLPPINPQR_
SUFU Phosphorylation S346 0.344 0.498 _KDS(ph)LESDSSTAIIPHELIR_
TCF7 Ubiquitylation K88 -0.867 -0.222 _ESLEEAAK(gl)R_
TCF7L1 Ubiquitylation K88 -0.867 -0.222 _ESLEEAAK(gl)R_
TCF7L2 Ubiquitylation K88 -0.867 -0.222 _ESLEEAAK(gl)R_
TP53 Ubiquitylation K120 -0.188 _LGFLHSGTAK(gl)SVTCTYSPALNK_
TP53 Ubiquitylation K164 0.157 -1.260 _AMAIYK(gl)QSQHMTEVVR_
TP53 Phosphorylation S314 -0.695 -1.000 _ALPNNTSS(ph)SPQPK_
TP53 Phosphorylation S315 -0.762 -0.959 _RALPNNTSSS(ph)PQPK_
TP53 Ubiquitylation K320 -0.978 _ALPNNTSSSPQPKK(gl)_
TP53 Ubiquitylation K357 -0.231 -0.823 _ELNEALELKDAQAGK(gl)EPGGSR_
WNT5A Ubiquitylation K268 -0.304 _VGDALK(gl)EK_


.

© Copyright Svejstrup Laboratory 2015