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PID_IL5_PATHWAY
(Pathway_654)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
LYN 1 -1.790 3.770
LYN 1 -1.790 3.770
PIK3CA 0
SDCBP 0 -1.190 2.010 -1.188 0.299
SDCBP 0 -1.190 2.010 -0.575
PIK3R1 0 1.910 -1.220 -0.441 0.147
STAT5B 0 0.670 -0.960
GRB2 0 -0.240 0.300 -1.021 0.057 0.906
PTPN11 0 -0.210 -0.400 0.644 1.053 0.451

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
GRB2 Ubiquitylation K10 0.146 _YDFK(gl)ATADDELSFK_
GRB2 Ubiquitylation K20 -0.078 _ATADDELSFK(gl)R_
GRB2 Ubiquitylation K69 -0.362 0.641 _AK(gl)AEEMLSK_
GRB2 Ubiquitylation K76 0.754 _AEEMLSK(gl)QR_
GRB2 Ubiquitylation K109 0.381 -0.002 _FGNDVQHFK(gl)VLR_
LYN Ubiquitylation K20 -0.592 _GKDSLSDDGVDLK(gl)TQPVR_
LYN Ubiquitylation K40 0.100 _DPTSNK(gl)QQRPVPESQLLPGQR_
LYN Phosphorylation S104 0.944 0.841 _DSLS(ph)DDGVDLK_
LYN Ubiquitylation K213 0.441 _HYQK(gl)QADGLCR_
LYN Ubiquitylation K477 -0.191 _VENCPDELYDIMK(gl)MCWK_
PIK3CA Ubiquitylation K864 0.390 0.588 _NSHTIM(ox)QIQCK(gl)GGLK_
PIK3CA Ubiquitylation K868 0.204 0.651 _NSHTIM(ox)QIQCKGGLK(gl)_
PIK3CA Ubiquitylation K974 -0.273 _GAQECTK(gl)TREFER_
PTPN11 Ubiquitylation K124 0.562 _EAEK(gl)LLTEK_
SDCBP Phosphorylation S6 0.120 0.427 _(ac)SLYPS(ph)LEDLKVDK_
SDCBP Ubiquitylation K35 -0.806 _(ac)SLYPSLEDLKVDK(gl)_
SDCBP Ubiquitylation K129 0.064 0.792 _RAEIK(gl)QGIR_
SDCBP Ubiquitylation K199 -0.134 -0.436 _VLK(gl)QAFGEK_
SDCBP Ubiquitylation K243 0.141 _ITSIVK(gl)DSSAAR_
STAT5B Phosphorylation S194 0.270 _IQAQFGPLAQLS(ph)PQER_


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