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Query: G3BP1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
G3BP1 0 2.700 -1.510 1.890
G3BP1 0 2.700 -1.510 1.890 0.496 1.155 0.123 -0.821 -0.258

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
G3BP1 Ubiquitylation K76 0.373 0.769 _VM(ox)SQNFTNCHTK(gl)IR_
G3BP1 Phosphorylation S232 -0.357 -0.128 _SSS(ph)PAPADIAQTVQEDLR_
G3BP1 Phosphorylation T241 -0.320 -0.238 _SSSPAPADIAQT(ph)VQEDLR_
G3BP1 Phosphorylation S149 -0.519 -0.267 _YQDEVFGGFVTEPQEES(ph)EEEVEEPEER_
G3BP1 Ubiquitylation K50 -0.885 -0.279 _NSSYVHGGLDSNGK(gl)PADAVYGQK_
G3BP1 Phosphorylation S231 -0.108 -0.356 _SS(ph)SPAPADIAQTVQEDLR_
G3BP1 Ubiquitylation K5 -0.296 _VMEK(gl)PSPLLVGR_
G3BP1 Ubiquitylation K64 0.737 _K(gl)VM(ox)SQNFTNCHTK_
G3BP1 Phosphorylation T143 -0.277 _YQDEVFGGFVT(ph)EPQEESEEEVEEPEER_
G3BP1 Phosphorylation S230 -0.445 _S(ph)SSPAPADIAQTVQEDLR_

Background Information for G3BP1:


Pubmed-G3BP1 »
Uniprot-G3BP1 »
Biogrid-G3BP1 »
ProteomicsDB-G3BP1 »

Tumorportal-G3BP1 »
COSMIC-G3BP1 »
GenomeRNAi-G3BP1 »
Genecards-G3BP1


Protein-protein Interactions for G3BP1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait EIF3A Cat. description Hein, Mann, Cell 2015
Category members IP bait FLNB Cat. description Hein, Mann, Cell 2015
Category members IP bait G3BP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait NPM1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL10 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL35 Cat. description Hein, Mann, Cell 2015
Category members IP bait RRBP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait G3BP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NUFIP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait USP10 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in G3BP1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members RRM_dom IPR000504 4.34
Category members NTF2 IPR002075 0
Category members Nuclear_transport_factor_2_euk IPR018222 0


Protein complexes (CORUM database) featuring G3BP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 5613 Emerin complex 25 Database 0.04


Categories featuring G3BP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0004003 ATP-dependent DNA helicase activity Database 4.66
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0004004 ATP-dependent RNA helicase activity Database 1.43
Category members GO Category GO:0003729 mRNA binding Database 1.38
Category members GO Category GO:0010494 cytoplasmic stress granule Database 1.32
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0004519 endonuclease activity Database 0
Category members GO Category GO:0006810 transport Database 0
Category members GO Category GO:0007265 Ras protein signal transduction Database 0


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