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Results for the Category
endonuclease activity
(GO:0004519)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
ERCC1 1 -1.720 3.820
ERCC1 1 -1.460 2.450
ZC3H12B 1 2.890 -1.110
PPP1R8 1 1.500 -0.440 -2.097 -1.198 -1.038 0.291
ERCC5 1 -2.410 5.420
PXDNL 1 -0.360 0.320
RPS3 1 -0.940 1.360 0.247 -0.394 0.032 -0.254 -0.093
PELO 1 2.410 -0.720 -0.492 -0.182 0.320 0.293 0.579
ENDOG 1 1.270 -0.970
ELAC2 0 1.350 -1.060 1.016 -0.070 0.041 -0.052 -0.053
MRE11A 0 1.600 -0.730 0.145 0.420
MRE11A 0 1.600 -0.730 0.023 0.453 0.150
PNKP 0 1.170 -0.260 -1.642 0.133 0.861
NTHL1 0 0.810 -0.080 1.191 1.167
N4BP2 0 1.000 -0.870
DIS3 0 0.150 -0.690
DIS3 0 0.150 -0.690 -0.335 -0.438 -0.111
APEX1 0 0.630 -0.180 -0.057 -0.077
OGG1 0 -0.290 1.020
ZRANB3 0 -0.760 1.140
PMS2 0 0.410 -0.450
G3BP1 0 -1.510 1.890 0.496 1.155 0.123 -0.821 -0.258
G3BP1 0 -1.510 1.890
EME1 0
EXOG 0 0.140 -0.220
FEN1 0 -1.360 2.210 0.895 1.036 -1.389 -0.361 -0.414
APEX2 0 -0.680 0.420
ENDOV 0 0.510 -0.290
CKAP5 0 0.237 -1.027 -0.242 -0.255 -0.192
ERCC4 0 1.257
EME2 0
TSN 0 1.120 -1.190

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
APEX1 Ubiquitylation K25 -0.227 _GAVAEDGDELRTEPEAKK(gl)_
APEX1 Ubiquitylation K58 -0.215 _TSPSGK(gl)PATLK_
APEX2 Ubiquitylation K371 0.281 -0.420 _VQTCQNK(gl)AQVR_
APEX2 Ubiquitylation K482 -0.126 _TVK(gl)KPGPNLGR_
CKAP5 Ubiquitylation K1075 1.056 _DQVLAMLEK(gl)AK_
CKAP5 Ubiquitylation K1077 1.056 _DQVLAMLEK(gl)AK_
DIS3 Ubiquitylation K337 -0.491 _TAVSEK(gl)MLKPTGR_
DIS3 Ubiquitylation K535 -0.201 _RGTTVYLCEK(gl)R_
ELAC2 Phosphorylation S199 0.318 _HQPWQS(ph)PERPLSR_
ELAC2 Ubiquitylation K260 -1.081 _GNFLVLKAK(gl)_
ELAC2 Ubiquitylation K476 -1.649 _SAQDGPAPAEK(gl)R_
ELAC2 Ubiquitylation K811 -1.528 _ELAGGLEDGEPQQK(gl)R_
EME1 Ubiquitylation K449 0.158 _AVAEAPFK(gl)_
EME1 Ubiquitylation K450 0.225 _AVAEAPFKK(gl)_
EME2 Ubiquitylation K72 0.929 _ALAQYPLK(gl)QYR_
ENDOG Ubiquitylation K76 0.472 2.088 _YGLPGLAQLK(gl)SR_
ENDOG Ubiquitylation K210 -0.409 _TEADGK(gl)SYVK_
ENDOG Ubiquitylation K214 -0.272 _SYVK(gl)YQVIGK_
ENDOG Ubiquitylation K290 -0.169 _AGSLK(gl)AITAGSK_
ENDOV Ubiquitylation K57 0.024 _VGGVDVSFVK(gl)GDSVR_
ERCC1 Ubiquitylation K162 -0.634 _LQSLGK(gl)NFALR_
ERCC1 Ubiquitylation K243 -0.245 _VTECLTTVK(gl)SVNK_
ERCC1 Ubiquitylation K281 -1.586 _EDLALCPGLGPQK(gl)AR_
ERCC5 Phosphorylation S766 -0.289 -0.748 _LKTEKEPDATPPS(ph)PR_
ERCC5 Phosphorylation S809 -0.115 0.693 _NAPAAVDEGSIS(ph)PR_
ERCC5 Ubiquitylation K858 0.818 1.193 _INSSTENSDEGLK(gl)VR_
ERCC5 Phosphorylation S951 -0.018 -0.048 _ELTPAS(ph)PTCTNSVSK_
ERCC5 Phosphorylation S988 0.598 1.186 _FDSSLLSS(ph)DDETK_
EXOG Ubiquitylation K44 0.879 _KLEELK(gl)AK_
FEN1 Ubiquitylation K354 1.109 _VTGSLSSAK(gl)R_
G3BP1 Ubiquitylation K5 -0.296 _VMEK(gl)PSPLLVGR_
G3BP1 Ubiquitylation K50 -0.885 -0.279 _NSSYVHGGLDSNGK(gl)PADAVYGQK_
G3BP1 Ubiquitylation K64 0.737 _K(gl)VM(ox)SQNFTNCHTK_
G3BP1 Ubiquitylation K76 0.373 0.769 _VM(ox)SQNFTNCHTK(gl)IR_
G3BP1 Phosphorylation T143 -0.277 _YQDEVFGGFVT(ph)EPQEESEEEVEEPEER_
G3BP1 Phosphorylation S149 -0.519 -0.267 _YQDEVFGGFVTEPQEES(ph)EEEVEEPEER_
G3BP1 Phosphorylation S230 -0.445 _S(ph)SSPAPADIAQTVQEDLR_
G3BP1 Phosphorylation S231 -0.108 -0.356 _SS(ph)SPAPADIAQTVQEDLR_
G3BP1 Phosphorylation S232 -0.357 -0.128 _SSS(ph)PAPADIAQTVQEDLR_
G3BP1 Phosphorylation T241 -0.320 -0.238 _SSSPAPADIAQT(ph)VQEDLR_
MRE11A Ubiquitylation K387 0.442 _FSQK(gl)FVDR_
N4BP2 Ubiquitylation K20 0.107 _TANPK(gl)EVVVSSVASR_
OGG1 Ubiquitylation K289 -2.026 _DYSWHPTTSQAK(gl)GPSPQTNK_
PELO Ubiquitylation K84 -0.130 _VK(gl)GTNIQENEYVK_
PELO Ubiquitylation K227 0.673 _EQFCDYMFQQAVK(gl)TDNK_
PELO Ubiquitylation K231 0.656 _TDNK(gl)LLLENR_
PELO Ubiquitylation K254 -1.255 _YSLK(gl)EALCDPTVASR_
PELO Ubiquitylation K270 0.419 -0.240 _LSDTK(gl)AAGEVK_
PMS2 Ubiquitylation K146 -0.403 _IIQK(gl)TPYPRPR_
PNKP Phosphorylation T118 -2.016 -2.084 _TPESQPDT(ph)PPGTPLVSQDEK_
PNKP Ubiquitylation K226 0.178 _GK(gl)LPAEEFK_
PPP1R8 Ubiquitylation K234 1.514 _NMVQTAVVPVK(gl)K_
PPP1R8 Ubiquitylation K235 1.514 _NMVQTAVVPVK(gl)K_
PXDNL Ubiquitylation K1317 -1.619 _AVTQESQK(gl)K_
PXDNL Ubiquitylation K1318 1.959 _AVTQESQKK(gl)_
RPS3 Ubiquitylation K7 -0.351 0.640 _(ac)AVQISK(gl)K(gl)R_
RPS3 Ubiquitylation K8 -0.271 0.892 _(ac)AVQISK(gl)K(gl)R_
RPS3 Ubiquitylation K10 -0.280 0.954 _K(gl)FVADGIFK_
RPS3 Ubiquitylation K62 0.377 1.170 _TQNVLGEK(gl)GRR_
RPS3 Ubiquitylation K75 0.306 0.997 _IRELTAVVQK(gl)R_
RPS3 Ubiquitylation K90 0.875 0.887 _FGFPEGSVELYAEK(gl)VATR_
RPS3 Ubiquitylation K132 2.406 1.406 _FIMESGAK(gl)GCEVVVSGK_
RPS3 Ubiquitylation K141 0.299 1.362 _GCEVVVSGK(gl)LR_
RPS3 Ubiquitylation K185 1.424 _QGVLGIK(gl)VK_
RPS3 Ubiquitylation K197 -0.785 0.209 _IMLPWDPTGK(gl)_
RPS3 Ubiquitylation K202 -0.633 _K(gl)PLPDHVSIVEPK_
RPS3 Phosphorylation T220 -0.052 -0.022 _DEILPT(ph)TPISEQK_
RPS3 Phosphorylation T221 -0.107 0.074 _DEILPTT(ph)PISEQK_
RPS3 Ubiquitylation K230 1.186 -0.281 _GGK(gl)PEPPAM(ox)PQPVPTA_
TSN Ubiquitylation K187 0.009 -0.244 _LLNLK(gl)NDSLR_
TSN Ubiquitylation K219 0.800 _GFNK(gl)ETAAACVEK_
ZC3H12B Phosphorylation T2 0.714 0.282 _(ac)M(ox)T(ph)ATAEVET(ph)PKM(ox)EK_
ZC3H12B Phosphorylation T4 0.714 0.282 _(ac)M(ox)T(ph)ATAEVET(ph)PKM(ox)EK_
ZC3H12B Phosphorylation T9 0.714 0.282 _(ac)M(ox)T(ph)ATAEVET(ph)PKM(ox)EK_
ZRANB3 Ubiquitylation K163 -0.845 _VVIVDESHYMK(gl)SR_
ZRANB3 Ubiquitylation K179 -1.035 _ILLPIVQK(gl)AR_


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