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Query: ELAC2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ELAC2 0 0.119 1.350 -1.060 1.016 -0.070 0.041 -0.052 -0.053

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ELAC2 Phosphorylation S199 0.318 _HQPWQS(ph)PERPLSR_
ELAC2 Ubiquitylation K260 -1.081 _GNFLVLKAK(gl)_
ELAC2 Ubiquitylation K811 -1.528 _ELAGGLEDGEPQQK(gl)R_
ELAC2 Ubiquitylation K476 -1.649 _SAQDGPAPAEK(gl)R_

Background Information for ELAC2:





Protein-protein Interactions for ELAC2

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BAG2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CAMKK1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL35 Cat. description Hein, Mann, Cell 2015
Category members IP bait ELAC2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRPL21 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait YBEY Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ELAC2

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Beta-lactamas-like IPR001279 0


Protein complexes (CORUM database) featuring ELAC2

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ELAC2

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0016787 hydrolase activity Database 0.22
Category members Disease phenotype Familial_prostate_cancer Familial prostate cancer Database 0.07
Category members Disease phenotype PROSTATE_CANCER PROSTATE CANCER Database 0
Category members GO Category GO:0004519 endonuclease activity Database 0
Category members GO Category GO:0046872 metal ion binding Database 0


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