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bioLOGIC Data

Query: EME1

RNAi screen result	RNAPII IP (PI)	CSB IP	CSB IP (PI)	Chrom.	Chrom. (PI)	Phosphorylation	Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:
Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen

Gene name	Point score	Z-score sums	RNAi high	RNAi low	RNAPII-IP (PI)	CSB-IP	CSB-IP (PI)	Chrom.	Chrom. (PI)
EME1	0	0.383

PTM Sites:
Back to Protein Results | Red/green: hit at lower/upper end of the respective screen

Gene name	PTM type	PTM site	UV	UV (PI)	Sequence
EME1	Ubiquitylation	K450		0.225	_AVAEAPFKK(gl)_
EME1	Ubiquitylation	K449	0.158		_AVAEAPFK(gl)_

Background Information for EME1:

Pubmed-EME1 »

Uniprot-EME1 »

Biogrid-EME1 »

ProteomicsDB-EME1 »

Tumorportal-EME1 »

COSMIC-EME1 »

GenomeRNAi-EME1 »

Genecards-EME1

Protein-protein Interactions for EME1

Show screen data for	Category Name and Description	Link to cat description	Data Source
Category members	IP bait CCDC88A	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait CNTROB	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait CUL1	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait HNRNPU	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait KIF18A	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait MUS81	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait NEK2	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait PARD6B	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait PML	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait SGOL2	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait SHOC2	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait SORT1	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait SPTLC2	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait SRP72	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait UGGT1	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait USF1;usf1	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait VWA9	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait YEATS4	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait APP	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait CCL22	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait IDO2	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait INTU	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait KLK5	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait MUS81	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait NEUROG3	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait RBM33	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait SNX21	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015

Protein Domains in EME1

	Domain name	Domain Description	TC-NER relevance -log10(p-value)
Category members	ERCC4_domain	IPR006166	0

Protein complexes (CORUM database) featuring EME1

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)

Categories featuring EME1

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)
Category members	GO Category	GO:0005515	protein binding	Database	INF
Category members	GO Category	GO:0006281	DNA repair	Database	INF
Category members	GO Category	GO:0005730	nucleolus	Database	13.38
Category members	GO Category	GO:0006310	DNA recombination	Database	3.14
Category members	GO Category	GO:0003677	DNA binding	Database	1.53
Category members	Pathway	Pathway_343	KEGG_HOMOLOGOUS_RECOMBINATION	0	0.12
Category members	GO Category	GO:0004518	nuclease activity	Database	0.09
Category members	GO Category	GO:0004519	endonuclease activity	Database	0
Category members	GO Category	GO:0046872	metal ion binding	Database	0