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Query: OGG1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
OGG1 0 -1.006 -0.290 1.020

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
OGG1 Ubiquitylation K289 -2.026 _DYSWHPTTSQAK(gl)GPSPQTNK_

Background Information for OGG1:


Pubmed-OGG1 »
Uniprot-OGG1 »
Biogrid-OGG1 »
ProteomicsDB-OGG1 »

Tumorportal-OGG1 »
COSMIC-OGG1 »
GenomeRNAi-OGG1 »
Genecards-OGG1


Protein-protein Interactions for OGG1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait APLNR Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in OGG1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members HhH-GPD_domain IPR003265 0
Category members DNA_glycosylase IPR011257 0


Protein complexes (CORUM database) featuring OGG1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring OGG1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0006281 DNA repair Database INF
Category members Pathway Pathway_338 REACTOME_DNA_REPAIR 0 8.18
Category members GO Category GO:0006289 nucleotide-excision repair Database 6.65
Category members GO Category GO:0016607 nuclear speck Database 4.84
Category members GO Category GO:0003684 damaged DNA binding Database 4.54
Category members GO Category GO:0016363 nuclear matrix Database 1.89
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0033158 regulation of protein import into nucleus, translocation Database 1.32
Category members GO Category GO:0008017 microtubule binding Database 0.79
Category members GO Category GO:0042493 response to drug Database 0.66
Category members Pathway Pathway_208 PID_TAP63_PATHWAY 0 0.52
Category members GO Category GO:0071276 cellular response to cadmium ion Database 0.13
Category members GO Category GO:0003824 catalytic activity Database 0.11
Category members GO Category GO:0045471 response to ethanol Database 0.1
Category members GO Category GO:0002526 acute inflammatory response Database 0.09
Category members GO Category GO:0009314 response to radiation Database 0.07
Category members GO Category GO:0006284 base-excision repair Database 0.04
Category members GO Category GO:0051593 response to folic acid Database 0.01
Category members Pathway Pathway_334 KEGG_BASE_EXCISION_REPAIR 0 0
Category members Pathway Pathway_335 REACTOME_BASE_EXCISION_REPAIR 0 0
Category members Pathway Pathway_337 REACTOME_RESOLUTION_OF_AP_SITES_VIA_THE_MULTIPLE_NUCLEOTIDE_PATCH_REPLACEMENT_PATHWAY 0 0
Category members Pathway Pathway_951 REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY 0 0
Category members Pathway Pathway_952 REACTOME_RESOLUTION_OF_AP_SITES_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY 0 0
Category members Disease phenotype RENAL_CELL_CARCINOMA_NONPAPILLARY RENAL CELL CARCINOMA NONPAPILLARY Database 0
Category members GO Category GO:0004519 endonuclease activity Database 0
Category members GO Category GO:0006285 base-excision repair, AP site formation Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0006979 response to oxidative stress Database 0
Category members GO Category GO:0019104 DNA N-glycosylase activity Database 0
Category members GO Category GO:0032355 response to estradiol Database 0
Category members GO Category GO:0045007 depurination Database 0


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