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Query: ENDOG

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ENDOG 1 2.561 1.270 -0.970

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ENDOG Ubiquitylation K76 0.472 2.088 _YGLPGLAQLK(gl)SR_
ENDOG Ubiquitylation K290 -0.169 _AGSLK(gl)AITAGSK_
ENDOG Ubiquitylation K214 -0.272 _SYVK(gl)YQVIGK_
ENDOG Ubiquitylation K210 -0.409 _TEADGK(gl)SYVK_

Background Information for ENDOG:





Protein-protein Interactions for ENDOG

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BAG4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DNAJA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EPHA8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EVL Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GRK6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HSPA8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ITLN1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ITLN2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NFYC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PCGF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRKACG Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SSSCA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TPM1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ENDOG

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members DNA/RNA_non-sp_Endonuclease IPR001604 0
Category members Extracellular_endonuc_su_A IPR020821 0


Protein complexes (CORUM database) featuring ENDOG

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ENDOG

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0006310 DNA recombination Database 3.14
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members Pathway Pathway_956 BIOCARTA_DNAFRAGMENT_PATHWAY 0 0.62
Category members GO Category GO:0006309 apoptotic DNA fragmentation Database 0.26
Category members GO Category GO:0043065 positive regulation of apoptotic process Database 0.26
Category members GO Category GO:0016787 hydrolase activity Database 0.22
Category members GO Category GO:0034612 response to tumor necrosis factor Database 0.21
Category members GO Category GO:0001701 in utero embryonic development Database 0.2
Category members GO Category GO:0046677 response to antibiotic Database 0.08
Category members Pathway Pathway_1012 BIOCARTA_MITOCHONDRIA_PATHWAY 0 0
Category members Pathway Pathway_572 KEGG_APOPTOSIS 0 0
Category members GO Category GO:0004519 endonuclease activity Database 0
Category members GO Category GO:0046872 metal ion binding Database 0


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