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Query: APEX2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
APEX2 0 0.281 -0.680 0.420

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
APEX2 Ubiquitylation K371 0.281 -0.420 _VQTCQNK(gl)AQVR_
APEX2 Ubiquitylation K482 -0.126 _TVK(gl)KPGPNLGR_

Background Information for APEX2:


Pubmed-APEX2 »
Uniprot-APEX2 »
Biogrid-APEX2 »
ProteomicsDB-APEX2 »

Tumorportal-APEX2 »
COSMIC-APEX2 »
GenomeRNAi-APEX2 »
Genecards-APEX2


Protein-protein Interactions for APEX2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait PCNA Cat. description Hein, Mann, Cell 2015
Category members IP bait APEX2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RETN Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in APEX2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members AP_endonuc_1 IPR004808 0
Category members Endo/exonuclease/phosphatase IPR005135 0
Category members Znf_GRF IPR010666 0


Protein complexes (CORUM database) featuring APEX2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring APEX2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0006281 DNA repair Database INF
Category members GO Category GO:0006310 DNA recombination Database 3.14
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0007049 cell cycle Database 0.69
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity Database 0.16
Category members GO Category GO:0005743 mitochondrial inner membrane Database 0.15
Category members GO Category GO:0004518 nuclease activity Database 0.09
Category members Pathway Pathway_334 KEGG_BASE_EXCISION_REPAIR 0 0
Category members GO Category GO:0004519 endonuclease activity Database 0
Category members GO Category GO:0004527 exonuclease activity Database 0


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