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Query: PPP1R8

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PPP1R8 1 -2.528 1.500 -0.440 -2.097 -1.198 -1.038 0.291

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PPP1R8 Ubiquitylation K234 1.514 _NMVQTAVVPVK(gl)K_
PPP1R8 Ubiquitylation K235 1.514 _NMVQTAVVPVK(gl)K_

Background Information for PPP1R8:


Pubmed-PPP1R8 »
Uniprot-PPP1R8 »
Biogrid-PPP1R8 »
ProteomicsDB-PPP1R8 »

Tumorportal-PPP1R8 »
COSMIC-PPP1R8 »
GenomeRNAi-PPP1R8 »
Genecards-PPP1R8


Protein-protein Interactions for PPP1R8
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait PPP1CB Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP1CC Cat. description Hein, Mann, Cell 2015
Category members IP bait CYP1A1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GTF2E2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HSPA8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PPP1CA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PPP1CC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRNP27 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait USP47 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PPP1R8
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members FHA_dom IPR000253 2.3
Category members SMAD_FHA_domain IPR008984 0.86


Protein complexes (CORUM database) featuring PPP1R8
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PPP1R8
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0008380 RNA splicing Database 10.77
Category members GO Category GO:0016607 nuclear speck Database 4.84
Category members GO Category GO:0005681 spliceosomal complex Database 3.88
Category members GO Category GO:0006397 mRNA processing Database 3.76
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0008599 protein phosphatase type 1 regulator activity Database 0.16
Category members GO Category GO:0008283 cell proliferation Database 0.06
Category members GO Category GO:0004865 protein serine/threonine phosphatase inhibitor activity Database 0.05
Category members GO Category GO:0004519 endonuclease activity Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0006401 RNA catabolic process Database 0


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