bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

bioLOGIC Data


Exact search


Query: PLCE1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
W
[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PLCE1 0 0.174 0.540 -0.070

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PLCE1 Phosphorylation S1096 -0.120 0.294 _GES(ph)GEVTDDEMATR_

Background Information for PLCE1:


Pubmed-PLCE1 »
Uniprot-PLCE1 »
Biogrid-PLCE1 »
ProteomicsDB-PLCE1 »

Tumorportal-PLCE1 »
COSMIC-PLCE1 »
GenomeRNAi-PLCE1 »
Genecards-PLCE1


Protein-protein Interactions for PLCE1
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in PLCE1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Ubiquitin-rel_dom IPR029071 1.79
Category members PI-PLC_fam IPR001192 0.03
Category members PLipase_C_Pinositol-sp_Y IPR001711 0.03
Category members PLipase_C_EF-hand-like IPR015359 0.03
Category members C2_dom IPR000008 0
Category members Ras-assoc IPR000159 0
Category members PLipase_C_PInositol-sp_X_dom IPR000909 0
Category members RASGEF_cat_dom IPR001895 0
Category members PLC-like_Pdiesterase_TIM-brl IPR017946 0
Category members Ras_GEF_dom IPR023578 0


Protein complexes (CORUM database) featuring PLCE1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PLCE1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0019899 enzyme binding Database 1.57
Category members GO Category GO:0017016 Ras GTPase binding Database 1.28
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0007264 small GTPase mediated signal transduction Database 0.37
Category members GO Category GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway Database 0.36
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0005622 intracellular Database 0.32
Category members Pathway Pathway_106 KEGG_INOSITOL_PHOSPHATE_METABOLISM 0 0.28
Category members GO Category GO:0007173 epidermal growth factor receptor signaling pathway Database 0.26
Category members GO Category GO:0004629 phospholipase C activity Database 0.23
Category members GO Category GO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway Database 0.18
Category members Pathway Pathway_685 PID_RAS_PATHWAY 0 0.14
Category members Pathway Pathway_233 KEGG_CALCIUM_SIGNALING_PATHWAY 0 0.13
Category members GO Category GO:0005509 calcium ion binding Database 0.11
Category members GO Category GO:0008283 cell proliferation Database 0.06
Category members GO Category GO:0048016 inositol phosphate-mediated signaling Database 0.03
Category members GO Category GO:0046578 regulation of Ras protein signal transduction Database 0.03
Category members GO Category GO:0045859 regulation of protein kinase activity Database 0.01
Category members Pathway Pathway_235 BIOCARTA_PLCE_PATHWAY 0 0.01
Category members Pathway Pathway_488 KEGG_PHOSPHATIDYLINOSITOL_SIGNALING_SYSTEM 0 0
Category members Disease phenotype Familial_idiopathic_steroid-resistant_nephrotic_syndrome_with_diffuse_mesangial_sclerosis Familial idiopathic steroid-resistant nephrotic syndrome with diffuse mesangial sclerosis Database 0
Category members Disease phenotype Familial_idiopathic_steroid-resistant_nephrotic_syndrome_with_focal_segmental_hyalinosis Familial idiopathic steroid-resistant nephrotic syndrome with focal segmental hyalinosis Database 0
Category members GO Category GO:0000139 Golgi membrane Database 0
Category members GO Category GO:0000187 activation of MAPK activity Database 0
Category members GO Category GO:0001558 regulation of cell growth Database 0
Category members GO Category GO:0004435 phosphatidylinositol phospholipase C activity Database 0
Category members GO Category GO:0005057 receptor signaling protein activity Database 0
Category members GO Category GO:0005085 guanyl-nucleotide exchange factor activity Database 0
Category members GO Category GO:0006629 lipid metabolic process Database 0
Category members GO Category GO:0006644 phospholipid metabolic process Database 0
Category members GO Category GO:0006651 diacylglycerol biosynthetic process Database 0
Category members GO Category GO:0006940 regulation of smooth muscle contraction Database 0
Category members GO Category GO:0007010 cytoskeleton organization Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0007204 positive regulation of cytosolic calcium ion concentration Database 0
Category members GO Category GO:0007265 Ras protein signal transduction Database 0
Category members GO Category GO:0007507 heart development Database 0
Category members GO Category GO:0008081 phosphoric diester hydrolase activity Database 0
Category members GO Category GO:0008277 regulation of G-protein coupled receptor protein signaling pathway Database 0
Category members GO Category GO:0016042 lipid catabolic process Database 0
Category members GO Category GO:0019722 calcium-mediated signaling Database 0
Category members GO Category GO:0032835 glomerulus development Database 0
Category members GO Category GO:0035556 intracellular signal transduction Database 0
Category members GO Category GO:0043647 inositol phosphate metabolic process Database 0


.

© Copyright Svejstrup Laboratory 2015