bioLOGIC Category
Results for the Category
Familial idiopathic steroid-resistant nephrotic syndrome with focal segmental hyalinosis
(Familial_idiopathic_steroid-resistant_nephrotic_syndrome_with_focal_segmental_hyalinosis)
| RNAi screen result
|
RNAPII IP (MG132) |
CSB IP |
CSB IP (MG132) |
Chrom. |
Chrom. (MG132) |
Ubi /Phospo |
Ubi /Phospho (MG132) |
| W |
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| Gene name |
MGoogle Score |
RNAi high |
RNAi low |
RNAPII-IP (MG132) |
CSB-IP |
CSB-IP (MG132) |
Chrom. |
Chrom. (MG132) |
|
ACTN4
|
2
|
-0.050
|
0.190
|
0.936
|
1.929
|
-1.407
|
0.572
|
0.293
|
|
INF2
|
1
|
-0.800
|
1.620
|
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INF2
|
1
|
1.730
|
-1.180
|
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ADCK4
|
0
|
1.510
|
-1.170
|
|
0.518
|
-0.525
|
|
|
|
PLCE1
|
0
|
0.540
|
-0.070
|
|
|
|
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CD2AP
|
0
|
-0.900
|
-0.330
|
1.125
|
-0.237
|
-0.281
|
-1.465
|
-1.354
|
| Gene name |
PTM type |
PTM site |
UV |
UV (MG132) |
Sequence |
|
ACTN4
|
Ubiquitylation
|
K125
|
|
1.906
|
_ALDFIASKGVK(gl)_
|
|
ACTN4
|
Ubiquitylation
|
K350
|
0.585
|
|
_VQEK(gl)CQLEINFNTLQTK_
|
|
ACTN4
|
Ubiquitylation
|
K417
|
|
0.789
|
_LDHLAEK(gl)FR_
|
|
ACTN4
|
Ubiquitylation
|
K592
|
-0.644
|
0.678
|
_EAILAIHK(gl)EAQR_
|
|
ACTN4
|
Ubiquitylation
|
K760
|
0.273
|
1.507
|
_DAK(gl)GISQEQMQEFR_
|
|
CD2AP
|
Ubiquitylation
|
K71
|
-0.241
|
0.187
|
_ETEFKDDSLPIK(gl)R_
|
|
CD2AP
|
Ubiquitylation
|
K226
|
0.603
|
|
_EGSVK(gl)LR_
|
|
CD2AP
|
Phosphorylation
|
S510
|
0.349
|
0.536
|
_FNGGHS(ph)PTHSPEK_
|
|
CD2AP
|
Phosphorylation
|
T512
|
|
0.845
|
_FNGGHS(ph)PTHSPEK_
|
|
INF2
|
Ubiquitylation
|
K571
|
-0.122
|
1.307
|
_LNWQK(gl)LPSNVAR_
|
|
INF2
|
Phosphorylation
|
S588
|
-0.743
|
0.276
|
_EHNSMWASLS(ph)SPDAEAVEPDFSSIER_
|
|
INF2
|
Phosphorylation
|
S589
|
|
0.279
|
_EHNSMWASLSS(ph)PDAEAVEPDFSSIER_
|
|
INF2
|
Ubiquitylation
|
K612
|
-1.329
|
-0.213
|
_LFSFPAAK(gl)PK_
|
|
INF2
|
Ubiquitylation
|
K614
|
|
-0.266
|
_LFSFPAAK(gl)PK_
|
|
INF2
|
Ubiquitylation
|
K637
|
0.191
|
1.601
|
_EITFLDAKK(gl)_
|
|
INF2
|
Phosphorylation
|
S1083
|
|
-1.063
|
_RSSWYVDAS(ph)DVLTTEDPQCPQPLEGAWPVTLGDAQALKPLK_
|
|
INF2
|
Phosphorylation
|
S1147
|
0.167
|
-0.076
|
_DPTSLLGVLQAEADS(ph)TSEGLEDAVHSR_
|
|
PLCE1
|
Phosphorylation
|
S1096
|
-0.120
|
0.294
|
_GES(ph)GEVTDDEMATR_
|
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