bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

bioLOGIC Data


Exact search


Query: PLD1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
W
[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PLD1 0 1.432 -0.150 -0.140

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PLD1 Ubiquitylation K547 0.453 1.120 _SIDDVDSK(gl)LK_
PLD1 Ubiquitylation K549 1.120 _SIDDVDSK(gl)LK_
PLD1 Ubiquitylation K501 -0.155 _LTDVGSVK(gl)R_
PLD1 Ubiquitylation K1000 -0.600 _NATIYDK(gl)VFR_

Background Information for PLD1:


Pubmed-PLD1 »
Uniprot-PLD1 »
Biogrid-PLD1 »
ProteomicsDB-PLD1 »

Tumorportal-PLD1 »
COSMIC-PLD1 »
GenomeRNAi-PLD1 »
Genecards-PLD1


Protein-protein Interactions for PLD1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ATP6AP2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CEP135 Cat. description Hein, Mann, Cell 2015
Category members IP bait CORO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait HSPH1 Cat. description Hein, Mann, Cell 2015
Category members IP bait ING3 Cat. description Hein, Mann, Cell 2015
Category members IP bait KLC2 Cat. description Hein, Mann, Cell 2015
Category members IP bait POLH Cat. description Hein, Mann, Cell 2015
Category members IP bait TMED2 Cat. description Hein, Mann, Cell 2015
Category members IP bait APBA2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C1orf186 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CACNG5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDH5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GPR156 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GPR77 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KCTD17 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MIER2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait OSBPL5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPACA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TEX264 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TNFRSF19 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait UBE2O Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZRANB2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PLD1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Phox IPR001683 0.24
Category members PH_domain IPR001849 0.14
Category members PLipase_D_euk IPR016555 0.11
Category members PLipase_D/transphosphatidylase IPR001736 0


Protein complexes (CORUM database) featuring PLD1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 2537 PKC-alpha-PLD1-PLC-gamma-2 signaling complex, lacritin stimulated Database 0


Categories featuring PLD1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members Pathway Pathway_724 PID_MTOR_4PATHWAY 0 2
Category members Pathway Pathway_579 PID_ERBB1_DOWNSTREAM_PATHWAY 0 1.97
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members Pathway Pathway_666 KEGG_ENDOCYTOSIS 0 1.25
Category members Pathway Pathway_295 PID_ARF6_TRAFFICKING_PATHWAY 0 0.9
Category members GO Category GO:0005765 lysosomal membrane Database 0.82
Category members Pathway Pathway_568 PID_CDC42_PATHWAY 0 0.68
Category members GO Category GO:0035091 phosphatidylinositol binding Database 0.62
Category members Pathway Pathway_651 BIOCARTA_RAS_PATHWAY 0 0.61
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members GO Category GO:0007264 small GTPase mediated signal transduction Database 0.37
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members Pathway Pathway_548 BIOCARTA_RAC1_PATHWAY 0 0.3
Category members GO Category GO:0005768 endosome Database 0.29
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members Pathway Pathway_514 ST_GAQ_PATHWAY 0 0.17
Category members Pathway Pathway_649 KEGG_PANCREATIC_CANCER 0 0.15
Category members GO Category GO:0003824 catalytic activity Database 0.11
Category members Pathway Pathway_499 KEGG_FC_GAMMA_R_MEDIATED_PHAGOCYTOSIS 0 0.1
Category members GO Category GO:0006935 chemotaxis Database 0.09
Category members GO Category GO:0050830 defense response to Gram-positive bacterium Database 0.09
Category members Pathway Pathway_296 PID_ARF6_DOWNSTREAM_PATHWAY 0 0.08
Category members Pathway Pathway_405 PID_ALPHA_SYNUCLEIN_PATHWAY 0 0.08
Category members Pathway Pathway_663 PID_IL8_CXCR1_PATHWAY 0 0.01
Category members Pathway Pathway_100 REACTOME_PHOSPHOLIPID_METABOLISM 0 0
Category members Pathway Pathway_161 REACTOME_GLYCEROPHOSPHOLIPID_BIOSYNTHESIS 0 0
Category members Pathway Pathway_24 KEGG_PATHWAYS_IN_CANCER 0 0
Category members Pathway Pathway_257 KEGG_GNRH_SIGNALING_PATHWAY 0 0
Category members Pathway Pathway_276 KEGG_GLYCEROPHOSPHOLIPID_METABOLISM 0 0
Category members Pathway Pathway_4 REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 0 0
Category members Pathway Pathway_482 REACTOME_SYNTHESIS_OF_PA 0 0
Category members Pathway Pathway_497 KEGG_ETHER_LIPID_METABOLISM 0 0
Category members Pathway Pathway_658 ST_GA13_PATHWAY 0 0
Category members Pathway Pathway_668 PID_RHOA_PATHWAY 0 0
Category members Pathway Pathway_725 ST_GA12_PATHWAY 0 0
Category members GO Category GO:0000139 Golgi membrane Database 0
Category members GO Category GO:0004630 phospholipase D activity Database 0
Category members GO Category GO:0006644 phospholipid metabolic process Database 0
Category members GO Category GO:0006654 phosphatidic acid biosynthetic process Database 0
Category members GO Category GO:0006655 phosphatidylglycerol biosynthetic process Database 0
Category members GO Category GO:0007154 cell communication Database 0
Category members GO Category GO:0007265 Ras protein signal transduction Database 0
Category members GO Category GO:0008152 metabolic process Database 0
Category members GO Category GO:0016042 lipid catabolic process Database 0
Category members GO Category GO:0031902 late endosome membrane Database 0
Category members GO Category GO:0046474 glycerophospholipid biosynthetic process Database 0
Category members GO Category GO:0070290 NAPE-specific phospholipase D activity Database 0


.

© Copyright Svejstrup Laboratory 2015