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Query: SUMO1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SUMO1 0 3.541 0.450 0.060 -0.088 0.599 0.276 0.608 0.499

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SUMO1 Phosphorylation S2 0.441 0.416 _(ac)S(ph)DQEAKPSTEDLGDKK_
SUMO1 Ubiquitylation K48 -0.241 -0.185 _LK(gl)ESYCQR_
SUMO1 Ubiquitylation K23 0.713 -0.346 _EGEYIK(gl)LK_
SUMO1 Ubiquitylation K16 -0.686 -1.532 _(ac)SDQEAKPSTEDLGDK(gl)KEGEYIK_
SUMO1 Ubiquitylation K17 -0.857 -1.847 _(ac)SDQEAKPSTEDLGDKK(gl)EGEYIK_
SUMO1 Ubiquitylation K7 -0.850 -1.885 _(ac)SDQEAK(gl)PSTEDLGDKK_
SUMO1 Ubiquitylation K37 0.417 _VIGQDSSEIHFK(gl)VK_
SUMO1 Ubiquitylation K45 0.975 _MTTHLK(gl)K_
SUMO1 Ubiquitylation K46 0.647 _K(gl)LKESYCQR_

Background Information for SUMO1:


Pubmed-SUMO1 »
Uniprot-SUMO1 »
Biogrid-SUMO1 »
ProteomicsDB-SUMO1 »

Tumorportal-SUMO1 »
COSMIC-SUMO1 »
GenomeRNAi-SUMO1 »
Genecards-SUMO1


Protein-protein Interactions for SUMO1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait KPNB1 Cat. description Hein, Mann, Cell 2015
Category members IP bait NUP107 Cat. description Hein, Mann, Cell 2015
Category members IP bait NUP153 Cat. description Hein, Mann, Cell 2015
Category members IP bait NUP155 Cat. description Hein, Mann, Cell 2015
Category members IP bait NUP98 Cat. description Hein, Mann, Cell 2015
Category members IP bait RANBP2 Cat. description Hein, Mann, Cell 2015
Category members IP bait RCC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SEH1L Cat. description Hein, Mann, Cell 2015
Category members IP bait UBE2I Cat. description Hein, Mann, Cell 2015


Protein Domains in SUMO1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Rad60/SUMO_like IPR022617 1.93
Category members Ubiquitin-rel_dom IPR029071 1.79
Category members Ubiquitin-like IPR000626 1.61


Protein complexes (CORUM database) featuring SUMO1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 5755 SUMO1-SUA1-UBA2 complex Database 0.49
Category members Corum 1056 ZNF198-SUMO1 complex Database 0
Category members Corum 5260 TCF4-CTNNB1-SUMO1-EP300-HADAC6 complex Database 0


Categories featuring SUMO1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0006281 DNA repair Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005643 nuclear pore Database 6.58
Category members GO Category GO:0016607 nuclear speck Database 4.84
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members GO Category GO:0031965 nuclear membrane Database 2.59
Category members GO Category GO:0031625 ubiquitin protein ligase binding Database 2.54
Category members GO Category GO:0016605 PML body Database 1.41
Category members Pathway Pathway_1254 PID_RANBP2_PATHWAY 0 1.33
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members Pathway Pathway_943 PID_HDAC_CLASSI_PATHWAY 0 1.08
Category members Pathway Pathway_699 REACTOME_INTERFERON_SIGNALING 0 0.86
Category members GO Category GO:0031334 positive regulation of protein complex assembly Database 0.69
Category members GO Category GO:0019221 cytokine-mediated signaling pathway Database 0.44
Category members GO Category GO:0030578 PML body organization Database 0.39
Category members GO Category GO:0008134 transcription factor binding Database 0.37
Category members Pathway Pathway_505 REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM 0 0.33
Category members GO Category GO:0016925 protein sumoylation Database 0.33
Category members Pathway Pathway_1143 PID_HDAC_CLASSII_PATHWAY 0 0.3
Category members GO Category GO:0030425 dendrite Database 0.26
Category members GO Category GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process Database 0.24
Category members GO Category GO:0060021 palate development Database 0.23
Category members GO Category GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity Database 0.18
Category members GO Category GO:0060334 regulation of interferon-gamma-mediated signaling pathway Database 0.07
Category members Pathway Pathway_1062 BIOCARTA_PML_PATHWAY 0 0.06
Category members GO Category GO:0045202 synapse Database 0.06
Category members GO Category GO:0019789 SUMO ligase activity Database 0.05
Category members GO Category GO:0016604 nuclear body Database 0.04
Category members GO Category GO:0043392 negative regulation of DNA binding Database 0.01
Category members Pathway Pathway_906 REACTOME_REGULATION_OF_IFNG_SIGNALING 0 0.01
Category members Pathway Pathway_1259 BIOCARTA_PARKIN_PATHWAY 0 0
Category members Pathway Pathway_898 REACTOME_INTERFERON_GAMMA_SIGNALING 0 0
Category members Disease phenotype Cleft_Lip_+/-_Cleft_Palate Cleft Lip +/- Cleft Palate Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0032880 regulation of protein localization Database 0
Category members GO Category GO:0060333 interferon-gamma-mediated signaling pathway Database 0


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