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REACTOME_REGULATION_OF_IFNG_SIGNALING
(Pathway_906)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
IFNGR1 0 -1.300 2.410
PIAS1 0 -1.020 1.720 -1.034 -0.678 0.471 -0.051 1.019
STAT1 0 -0.550 0.170
SUMO1 0 0.450 0.060 -0.088 0.599 0.276 0.608 0.499
JAK1 0 0.190 -0.100 -1.504 -0.381 -0.438
PTPN2 0 1.210 -0.730
PTPN1 0 -0.150 0.310 1.066 0.459 0.251 0.322 0.379

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
IFNGR1 Ubiquitylation K299 -0.875 -0.201 _SATLETK(gl)PESK_
JAK1 Ubiquitylation K227 -0.405 _YIPETLNK(gl)SIR_
JAK1 Ubiquitylation K249 0.116 0.771 _DFLK(gl)EFNNK_
JAK1 Ubiquitylation K559 -0.478 _EISNLLVATK(gl)K_
PIAS1 Ubiquitylation K60 -1.191 _AGCSPAVQMKIK(gl)_
PIAS1 Ubiquitylation K341 -1.248 _VSLLCPLGK(gl)MR_
PIAS1 Phosphorylation S490 -0.898 -0.944 _RTCPSLSPTS(ph)PLNNK_
PIAS1 Phosphorylation S505 0.198 -0.250 _GILSLPHQAS(ph)PVSR_
PTPN1 Phosphorylation S352 0.032 _GS(ph)PLNAAPYGIESMSQDTEVR_
PTPN1 Phosphorylation S365 -0.247 0.956 _GSPLNAAPYGIESMS(ph)QDTEVR_
PTPN1 Phosphorylation S378 1.462 1.262 _VVGGS(ph)LR_
PTPN2 Phosphorylation S304 -0.873 -0.641 _ELSKEDLSPAFDHS(ph)PNK_
STAT1 Phosphorylation S727 1.377 0.974 _LQTTDNLLPMS(ph)PEEFDEVSR_
SUMO1 Phosphorylation S2 0.441 0.416 _(ac)S(ph)DQEAKPSTEDLGDKK_
SUMO1 Ubiquitylation K7 -0.850 -1.885 _(ac)SDQEAK(gl)PSTEDLGDKK_
SUMO1 Ubiquitylation K16 -0.686 -1.532 _(ac)SDQEAKPSTEDLGDK(gl)KEGEYIK_
SUMO1 Ubiquitylation K17 -0.857 -1.847 _(ac)SDQEAKPSTEDLGDKK(gl)EGEYIK_
SUMO1 Ubiquitylation K23 0.713 -0.346 _EGEYIK(gl)LK_
SUMO1 Ubiquitylation K37 0.417 _VIGQDSSEIHFK(gl)VK_
SUMO1 Ubiquitylation K45 0.975 _MTTHLK(gl)K_
SUMO1 Ubiquitylation K46 0.647 _K(gl)LKESYCQR_
SUMO1 Ubiquitylation K48 -0.241 -0.185 _LK(gl)ESYCQR_


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