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Query: HSPBP1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
HSPBP1 1 4.182 0.630 -0.340 -0.096 -0.788 0.132 2.885 1.233

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
HSPBP1 Phosphorylation S397 0.212 1.127 _LLQTCFSS(ph)PADDSMDR_
HSPBP1 Ubiquitylation K140 -0.036 _EEVEQMK(gl)SCLR_
HSPBP1 Ubiquitylation K291 -0.487 _AMQQQVQK(gl)LK_

Background Information for HSPBP1:


Pubmed-HSPBP1 »
Uniprot-HSPBP1 »
Biogrid-HSPBP1 »
ProteomicsDB-HSPBP1 »

Tumorportal-HSPBP1 »
COSMIC-HSPBP1 »
GenomeRNAi-HSPBP1 »
Genecards-HSPBP1


Protein-protein Interactions for HSPBP1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ARMC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C21orf59 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C3orf37 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCDC117 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DGCR14 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ELF1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FLYWCH2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GMNN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HSPA8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HSPBP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait METTL21A Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in HSPBP1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26


Protein complexes (CORUM database) featuring HSPBP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring HSPBP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005488 binding Database 9.32
Category members GO Category GO:0006457 protein folding Database 4.93
Category members GO Category GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process Database 0.24
Category members GO Category GO:0004857 enzyme inhibitor activity Database 0
Category members GO Category GO:0031398 positive regulation of protein ubiquitination Database 0
Category members GO Category GO:0043086 negative regulation of catalytic activity Database 0


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