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Query: BBS7

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
BBS7 0 -0.505

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
BBS7 Ubiquitylation K685 -0.505 _FK(gl)GTNVK_
BBS7 Ubiquitylation K479 -0.952 _IQPK(gl)TCQVR_
BBS7 Ubiquitylation K59 -1.507 _KGEAAAVFK(gl)TLPGPK_

Background Information for BBS7:


Pubmed-BBS7 »
Uniprot-BBS7 »
Biogrid-BBS7 »
ProteomicsDB-BBS7 »

Tumorportal-BBS7 »
COSMIC-BBS7 »
GenomeRNAi-BBS7 »
Genecards-BBS7


Protein-protein Interactions for BBS7
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BBS1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BBS12 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BBS5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BBS7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LRRC27 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LZTFL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NME3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SCGN Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in BBS7
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members WD40_repeat_dom IPR017986 1.39


Protein complexes (CORUM database) featuring BBS7
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring BBS7
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0015031 protein transport Database 3.48
Category members GO Category GO:0007224 smoothened signaling pathway Database 2.11
Category members GO Category GO:0005813 centrosome Database 0.75
Category members GO Category GO:0008104 protein localization Database 0.5
Category members GO Category GO:0001103 RNA polymerase II repressing transcription factor binding Database 0.36
Category members GO Category GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process Database 0.24
Category members GO Category GO:0060021 palate development Database 0.23
Category members GO Category GO:0006357 regulation of transcription from RNA polymerase II promoter Database 0.19
Category members GO Category GO:0034464 BBSome Database 0.1
Category members GO Category GO:0001947 heart looping Database 0.08
Category members Disease phenotype BARDET-BIEDL_SYNDROME BARDET-BIEDL SYNDROME Database 0
Category members GO Category GO:0001654 eye development Database 0
Category members GO Category GO:0007368 determination of left/right symmetry Database 0
Category members GO Category GO:0007420 brain development Database 0
Category members GO Category GO:0007507 heart development Database 0
Category members GO Category GO:0007601 visual perception Database 0
Category members GO Category GO:0032402 melanosome transport Database 0
Category members GO Category GO:0035058 nonmotile primary cilium assembly Database 0
Category members GO Category GO:0045444 fat cell differentiation Database 0
Category members GO Category GO:0048546 digestive tract morphogenesis Database 0
Category members GO Category GO:0051877 pigment granule aggregation in cell center Database 0
Category members GO Category GO:0060170 ciliary membrane Database 0
Category members GO Category GO:0060173 limb development Database 0
Category members GO Category GO:0060271 cilium morphogenesis Database 0


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