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Query: TAF1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TAF1 0 2.542 0.381 0.385

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TAF1 Phosphorylation S1176 0.662 1.114 _DDDTASVTS(ph)LNSSATGR_
TAF1 Phosphorylation T1703 0.001 -0.298 _DASVFQDESNM(ox)SVLDIPSAT(ph)PEK_
TAF1 Phosphorylation S547 -1.176 _LLEPPVLTLDPNDENLILEIPDEKEEATSNSPS(ph)K_
TAF1 Phosphorylation S550 -1.343 _LLEPPVLTLDPNDENLILEIPDEKEEATSNSPSKES(ph)K_

Background Information for TAF1:


Pubmed-TAF1 »
Uniprot-TAF1 »
Biogrid-TAF1 »
ProteomicsDB-TAF1 »

Tumorportal-TAF1 »
COSMIC-TAF1 »
GenomeRNAi-TAF1 »
Genecards-TAF1


Protein-protein Interactions for TAF1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ATM Cat. description Hein, Mann, Cell 2015
Category members IP bait CD14 Cat. description Hein, Mann, Cell 2015
Category members IP bait CHMP4B Cat. description Hein, Mann, Cell 2015
Category members IP bait GAR1 Cat. description Hein, Mann, Cell 2015
Category members IP bait JAK3 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYC Cat. description Hein, Mann, Cell 2015
Category members IP bait TINF2 Cat. description Hein, Mann, Cell 2015
Category members IP bait TMEM248 Cat. description Hein, Mann, Cell 2015
Category members IP bait TP53BP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait TAF7L Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TAF8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TAF1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Bromodomain IPR001487 1.43


Protein complexes (CORUM database) featuring TAF1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1257 ALL-1 supercomplex Database 4.3
Category members Corum 5386 MLL1-WDR5 complex Database 0.31
Category members Corum 1401 MOF complex Database 0.09
Category members Corum 493 DAB complex Database 0.04
Category members Corum 1318 Transcription initiation factor complex (TAF1, TAF5, TAF11, TAF12, TBP) Database 0
Category members Corum 155 TFIID complex Database 0
Category members Corum 3009 TFIID complex Database 0
Category members Corum 463 TFIID-beta complex Database 0
Category members Corum 469 TFIID-beta complex Database 0
Category members Corum 484 TFIID complex Database 0
Category members Corum 485 TFIID complex, B-cell specific Database 0
Category members Corum 492 DA complex Database 0
Category members Corum 508 TFIID complex Database 0
Category members Corum 509 TFIID complex Database 0
Category members Corum 514 TFIID-beta complex Database 0


Categories featuring TAF1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0016032 viral process Database INF
Category members Pathway Pathway_197 REACTOME_HIV_INFECTION 0 12.07
Category members Pathway Pathway_376 REACTOME_HIV_LIFE_CYCLE 0 9.45
Category members Pathway Pathway_348 REACTOME_TRANSCRIPTION 0 9
Category members GO Category GO:0019048 modulation by virus of host morphology or physiology Database 7.81
Category members Pathway Pathway_374 REACTOME_LATE_PHASE_OF_HIV_LIFE_CYCLE 0 7.57
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0006352 DNA-dependent transcription, initiation Database 3.76
Category members GO Category GO:0003713 transcription coactivator activity Database 3.68
Category members GO Category GO:0006974 cellular response to DNA damage stimulus Database 3.57
Category members Pathway Pathway_375 REACTOME_RNA_POL_II_TRANSCRIPTION 0 2.46
Category members GO Category GO:0002039 p53 binding Database 2.06
Category members GO Category GO:0006368 transcription elongation from RNA polymerase II promoter Database 2.03
Category members Pathway Pathway_363 REACTOME_RNA_POL_II_PRE_TRANSCRIPTION_EVENTS 0 1.84
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0016573 histone acetylation Database 1.24
Category members GO Category GO:0006366 transcription from RNA polymerase II promoter Database 0.96
Category members GO Category GO:0070577 histone acetyl-lysine binding Database 0.88
Category members GO Category GO:0004674 protein serine/threonine kinase activity Database 0.66
Category members GO Category GO:0004402 histone acetyltransferase activity Database 0.56
Category members GO Category GO:0071339 MLL1 complex Database 0.45
Category members GO Category GO:0008134 transcription factor binding Database 0.37
Category members GO Category GO:0017025 TBP-class protein binding Database 0.35
Category members Pathway Pathway_370 REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING 0 0.34
Category members GO Category GO:0006367 transcription initiation from RNA polymerase II promoter Database 0.25
Category members GO Category GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process Database 0.24
Category members GO Category GO:0046777 protein autophosphorylation Database 0.23
Category members Pathway Pathway_406 PID_RB_1PATHWAY 0 0.21
Category members GO Category GO:0043565 sequence-specific DNA binding Database 0.18
Category members GO Category GO:0018105 peptidyl-serine phosphorylation Database 0.18
Category members Pathway Pathway_759 BIOCARTA_P53HYPOXIA_PATHWAY 0 0.18
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members GO Category GO:0018107 peptidyl-threonine phosphorylation Database 0.01
Category members GO Category GO:0044212 transcription regulatory region DNA binding Database 0
Category members Pathway Pathway_856 KEGG_BASAL_TRANSCRIPTION_FACTORS 0 0
Category members GO Category GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle Database 0
Category members GO Category GO:0005669 transcription factor TFIID complex Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly Database 0
Category members GO Category GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter Database 0


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