Results for the Category
negative regulation of smooth muscle cell proliferation
(GO:0048662)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| COMT | 1 | -2.310 | 4.960 | 0.523 | 0.939 | |||
| MFN2 | 1 | 0.100 | 0.320 | 0.028 | ||||
| ILK | 1 | -1.560 | 3.680 | -0.463 | -0.527 | |||
| HMOX1 | 0 | 0.330 | 0.220 | -1.817 | -1.289 | |||
| TNFAIP3 | 0 | 0.760 | -0.500 | |||||
| NDRG2 | 0 | -0.250 | 0.880 | |||||
| SF1 | 0 | -1.650 | 2.470 | -0.710 | ||||
| SF1 | 0 | -1.650 | 2.470 | -0.461 | ||||
| SF1 | 0 | -1.650 | 2.470 | -0.405 | -0.524 | -0.618 | -1.262 | -0.522 |
| TRIB1 | 0 | -0.220 | -0.430 | |||||
| CTNNBIP1 | 0 | 0.180 | -0.150 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| COMT | Ubiquitylation | K159 | -0.475 | 0.002 | _MVDFAGVK(gl)DK_ |
| COMT | Ubiquitylation | K161 | -0.475 | 0.002 | _MVDFAGVK(gl)DK_ |
| CTNNBIP1 | Ubiquitylation | K19 | -1.489 | _EGAPGKSPEEMYIQQK(gl)VR_ | |
| HMOX1 | Ubiquitylation | K243 | -0.972 | _ASNK(gl)VQDSAPVETPR_ | |
| HMOX1 | Ubiquitylation | K256 | -1.769 | _GK(gl)PPLNTR_ | |
| ILK | Ubiquitylation | K85 | -0.777 | _DIVQK(gl)LLQYK_ | |
| ILK | Ubiquitylation | K426 | -0.300 | _LMK(gl)ICMNEDPAK_ | |
| ILK | Ubiquitylation | K435 | -2.732 | _ICMNEDPAK(gl)RPK_ | |
| MFN2 | Ubiquitylation | K84 | 1.579 | 0.761 | _GYLSK(gl)VR_ |
| MFN2 | Ubiquitylation | K316 | -0.574 | _IQK(gl)AQGMPEGGGALAEGFQVR_ | |
| MFN2 | Ubiquitylation | K357 | 0.235 | -0.035 | _TK(gl)FEQHTVR_ |
| MFN2 | Ubiquitylation | K366 | -0.376 | _AK(gl)QIAEAVR_ | |
| MFN2 | Ubiquitylation | K416 | -0.150 | 0.279 | _QLELLAQDYK(gl)LR_ |
| MFN2 | Ubiquitylation | K420 | 1.342 | 0.355 | _IK(gl)QITEEVER_ |
| MFN2 | Ubiquitylation | K463 | -0.905 | _VYK(gl)NELHR_ | |
| MFN2 | Ubiquitylation | K560 | -0.434 | _FLGPK(gl)NSRR_ | |
| MFN2 | Ubiquitylation | K719 | -0.768 | _ENLEQEIAAMNK(gl)K_ | |
| MFN2 | Ubiquitylation | K720 | -0.575 | _ENLEQEIAAMNKK(gl)_ | |
| MFN2 | Ubiquitylation | K730 | -1.137 | _KIEVLDSLQSK(gl)AK_ | |
| NDRG2 | Phosphorylation | S328 | 0.778 | -0.121 | _S(ph)RTASLTSAASVDGNR_ |
| NDRG2 | Phosphorylation | S332 | 0.366 | 0.448 | _TAS(ph)LTSAASVDGNR_ |
| NDRG2 | Phosphorylation | S338 | 0.765 | -0.768 | _TASLTSAAS(ph)VDGNR_ |
| SF1 | Ubiquitylation | K78 | 0.110 | _NIEKECNAK(gl)IMIR_ | |
| SF1 | Phosphorylation | S80 | -1.127 | -1.226 | _TGDLGIPPNPEDRS(ph)PS(ph)PEPIYNSEGK_ |
| SF1 | Phosphorylation | S82 | -1.197 | -0.218 | _SPS(ph)PEPIYNSEGK_ |
| SF1 | Ubiquitylation | K131 | 0.313 | 0.887 | _NILK(gl)QGIETPEDQNDLRK_ |
| SF1 | Phosphorylation | S181 | -0.584 | _YACGLWGLS(ph)PASR_ | |
| TNFAIP3 | Ubiquitylation | K722 | 0.496 | 0.176 | _ASCK(gl)NILACR_ |
| TRIB1 | Ubiquitylation | K46 | -2.031 | -0.877 | _LLDADDAAAVAAK(gl)CPR_ |
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