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Query: SF1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SF1 0 0.937 -1.650 2.470 -0.461
SF1 0 0.937 -1.650 2.470 -0.710
SF1 0 0.937 -1.650 2.470 -0.405 -0.524 -0.618 -1.262 -0.522

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SF1 Ubiquitylation K131 0.313 0.887 _NILK(gl)QGIETPEDQNDLRK_
SF1 Phosphorylation S82 -1.197 -0.218 _SPS(ph)PEPIYNSEGK_
SF1 Phosphorylation S181 -0.584 _YACGLWGLS(ph)PASR_
SF1 Phosphorylation S80 -1.127 -1.226 _TGDLGIPPNPEDRS(ph)PS(ph)PEPIYNSEGK_
SF1 Ubiquitylation K78 0.110 _NIEKECNAK(gl)IMIR_

Background Information for SF1:


Pubmed-SF1 »
Uniprot-SF1 »
Biogrid-SF1 »
ProteomicsDB-SF1 »

Tumorportal-SF1 »
COSMIC-SF1 »
GenomeRNAi-SF1 »
Genecards-SF1


Protein-protein Interactions for SF1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait AMOT Cat. description Hein, Mann, Cell 2015
Category members IP bait CDC42 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDKN2AIP Cat. description Hein, Mann, Cell 2015
Category members IP bait CHMP4C Cat. description Hein, Mann, Cell 2015
Category members IP bait CSNK2A2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CUL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait DYNC1LI1 Cat. description Hein, Mann, Cell 2015
Category members IP bait EMC2 Cat. description Hein, Mann, Cell 2015
Category members IP bait ITGB1 Cat. description Hein, Mann, Cell 2015
Category members IP bait ITSN2 Cat. description Hein, Mann, Cell 2015
Category members IP bait JUNB Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF19 Cat. description Hein, Mann, Cell 2015
Category members IP bait KLC3 Cat. description Hein, Mann, Cell 2015
Category members IP bait LLGL2 Cat. description Hein, Mann, Cell 2015
Category members IP bait MAPK8 Cat. description Hein, Mann, Cell 2015
Category members IP bait NAA11 Cat. description Hein, Mann, Cell 2015
Category members IP bait PARD6B Cat. description Hein, Mann, Cell 2015
Category members IP bait PDLIM5 Cat. description Hein, Mann, Cell 2015
Category members IP bait PFDN2 Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP2R1A Cat. description Hein, Mann, Cell 2015
Category members IP bait PRKCZ Cat. description Hein, Mann, Cell 2015
Category members IP bait RNF41 Cat. description Hein, Mann, Cell 2015
Category members IP bait SAMHD1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SGOL2 Cat. description Hein, Mann, Cell 2015
Category members IP bait TRAPPC8 Cat. description Hein, Mann, Cell 2015
Category members IP bait TUBA3C;TUBA3E Cat. description Hein, Mann, Cell 2015
Category members IP bait TUBG1 Cat. description Hein, Mann, Cell 2015
Category members IP bait BCHE Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CAPN13 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HAO2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HSPBP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NAGK Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait P4HA3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SFPQ Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SF1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Znf_CCHC IPR001878 1.51
Category members KH_dom IPR004087 0.23
Category members KH_dom_type_1 IPR004088 0.13


Protein complexes (CORUM database) featuring SF1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 351 Spliceosome Database 9.3


Categories featuring SF1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005840 ribosome Database 12.2
Category members GO Category GO:0000398 mRNA splicing, via spliceosome Database 7.06
Category members GO Category GO:0005681 spliceosomal complex Database 3.88
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0000245 spliceosomal complex assembly Database 0.39
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0000389 mRNA 3'-splice site recognition Database 0
Category members GO Category GO:0003714 transcription corepressor activity Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0022402 cell cycle process Database 0
Category members GO Category GO:0030238 male sex determination Database 0
Category members GO Category GO:0033327 Leydig cell differentiation Database 0
Category members GO Category GO:0048662 negative regulation of smooth muscle cell proliferation Database 0
Category members GO Category GO:0050810 regulation of steroid biosynthetic process Database 0


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