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Query: NDRG2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
NDRG2 0 2.106 -0.250 0.880

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
NDRG2 Phosphorylation S332 0.366 0.448 _TAS(ph)LTSAASVDGNR_
NDRG2 Phosphorylation S328 0.778 -0.121 _S(ph)RTASLTSAASVDGNR_
NDRG2 Phosphorylation S338 0.765 -0.768 _TASLTSAAS(ph)VDGNR_

Background Information for NDRG2:


Pubmed-NDRG2 »
Uniprot-NDRG2 »
Biogrid-NDRG2 »
ProteomicsDB-NDRG2 »

Tumorportal-NDRG2 »
COSMIC-NDRG2 »
GenomeRNAi-NDRG2 »
Genecards-NDRG2


Protein-protein Interactions for NDRG2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CDK15 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DDX19B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NDRG2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in NDRG2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members NDRG IPR004142 0
Category members AB_hydrolase IPR029058 0


Protein complexes (CORUM database) featuring NDRG2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring NDRG2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0030426 growth cone Database 1.61
Category members GO Category GO:0005813 centrosome Database 0.75
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members Pathway Pathway_142 PID_MYC_REPRESS_PATHWAY 0 0.21
Category members GO Category GO:0016055 Wnt signaling pathway Database 0.11
Category members GO Category GO:0070373 negative regulation of ERK1 and ERK2 cascade Database 0.1
Category members GO Category GO:0003674 molecular_function Database 0.08
Category members GO Category GO:0030154 cell differentiation Database 0.06
Category members GO Category GO:0001818 negative regulation of cytokine production Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0007399 nervous system development Database 0
Category members GO Category GO:0010574 regulation of vascular endothelial growth factor production Database 0
Category members GO Category GO:0048662 negative regulation of smooth muscle cell proliferation Database 0


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