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Query: KAT6A

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
KAT6A 1 4.104 0.100 -0.500 0.334 0.461

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
KAT6A Phosphorylation S473 2.569 _LFGS(ph)QEIMTEK_
KAT6A Phosphorylation S1090 0.740 1.024 _RLSS(ph)QDVLR_
KAT6A Phosphorylation S1089 0.499 0.643 _RLS(ph)SQDVLR_
KAT6A Phosphorylation S1001 -0.884 -0.411 _SSS(ph)PPILTKPTLK_
KAT6A Phosphorylation S1113 -0.700 _SKDEEEDEES(ph)DDADDTPILKPVSLLR_

Background Information for KAT6A:


Pubmed-KAT6A »
Uniprot-KAT6A »
Biogrid-KAT6A »
ProteomicsDB-KAT6A »

Tumorportal-KAT6A »
COSMIC-KAT6A »
GenomeRNAi-KAT6A »
Genecards-KAT6A


Protein-protein Interactions for KAT6A
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait KAT6A Cat. description Hein, Mann, Cell 2015


Protein Domains in KAT6A
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Znf_FYVE_PHD IPR011011 1.23
Category members Znf_PHD IPR001965 1.15
Category members Znf_PHD-finger IPR019787 0.91
Category members Histone_H1/H5_H15 IPR005818 0.14
Category members MOZ_SAS IPR002717 0.02
Category members Acyl_CoA_acyltransferase IPR016181 0


Protein complexes (CORUM database) featuring KAT6A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 2859 ING5 complex Database 0.56


Categories featuring KAT6A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members GO Category GO:0003682 chromatin binding Database 6.07
Category members GO Category GO:0006334 nucleosome assembly Database 3.77
Category members GO Category GO:0003713 transcription coactivator activity Database 3.68
Category members GO Category GO:0000786 nucleosome Database 2.41
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0016605 PML body Database 1.41
Category members GO Category GO:0016573 histone acetylation Database 1.24
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0004402 histone acetyltransferase activity Database 0.56
Category members GO Category GO:0070776 MOZ/MORF histone acetyltransferase complex Database 0.45
Category members GO Category GO:0008134 transcription factor binding Database 0.37
Category members GO Category GO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups Database 0.33
Category members GO Category GO:0006473 protein acetylation Database 0.3
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0045893 positive regulation of transcription, DNA-dependent Database 0.28
Category members GO Category GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity Database 0.18
Category members GO Category GO:0035162 embryonic hemopoiesis Database 0.17
Category members GO Category GO:0016407 acetyltransferase activity Database 0.05
Category members Disease phenotype Acute_myeloid_leukemia_with_t(8;16)(p11;p13)_translocation Acute myeloid leukemia with t(8;16)(p11;p13) translocation Database 0
Category members GO Category GO:0003007 heart morphogenesis Database 0
Category members GO Category GO:0006323 DNA packaging Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0030099 myeloid cell differentiation Database 0
Category members GO Category GO:0035019 somatic stem cell maintenance Database 0
Category members GO Category GO:0035909 aorta morphogenesis Database 0
Category members GO Category GO:0043966 histone H3 acetylation Database 0
Category members GO Category GO:0060325 face morphogenesis Database 0


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