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Query: PROX1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PROX1 0 0.962 0.800 -0.550

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PROX1 Phosphorylation S511 0.460 0.502 _DRAS(ph)PESLDLTR_

Background Information for PROX1:


Pubmed-PROX1 »
Uniprot-PROX1 »
Biogrid-PROX1 »
ProteomicsDB-PROX1 »

Tumorportal-PROX1 »
COSMIC-PROX1 »
GenomeRNAi-PROX1 »
Genecards-PROX1


Protein-protein Interactions for PROX1
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in PROX1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Homeodomain-like IPR009057 0
Category members Homeo_prospero_dom IPR023082 0


Protein complexes (CORUM database) featuring PROX1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PROX1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members GO Category GO:0006366 transcription from RNA polymerase II promoter Database 0.96
Category members GO Category GO:0016922 ligand-dependent nuclear receptor binding Database 0.89
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members GO Category GO:0001889 liver development Database 0.51
Category members GO Category GO:0030324 lung development Database 0.39
Category members GO Category GO:0055005 ventricular cardiac myofibril assembly Database 0.32
Category members GO Category GO:0007275 multicellular organismal development Database 0.31
Category members GO Category GO:0008285 negative regulation of cell proliferation Database 0.28
Category members GO Category GO:0045893 positive regulation of transcription, DNA-dependent Database 0.28
Category members GO Category GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity Database 0.18
Category members GO Category GO:0043565 sequence-specific DNA binding Database 0.18
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members GO Category GO:0030910 olfactory placode formation Database 0.07
Category members GO Category GO:0021542 dentate gyrus development Database 0.06
Category members GO Category GO:0045787 positive regulation of cell cycle Database 0.04
Category members GO Category GO:0021707 cerebellar granule cell differentiation Database 0.04
Category members GO Category GO:0070365 hepatocyte differentiation Database 0.03
Category members GO Category GO:0045737 positive regulation of cyclin-dependent protein kinase activity Database 0.03
Category members GO Category GO:0021915 neural tube development Database 0.03
Category members GO Category GO:0000122 negative regulation of transcription from RNA polymerase II promoter Database 0.02
Category members GO Category GO:0002089 lens morphogenesis in camera-type eye Database 0.01
Category members GO Category GO:0031016 pancreas development Database 0.01
Category members GO Category GO:0044212 transcription regulatory region DNA binding Database 0
Category members GO Category GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity Database 0
Category members GO Category GO:0001709 cell fate determination Database 0
Category members GO Category GO:0001822 kidney development Database 0
Category members GO Category GO:0001938 positive regulation of endothelial cell proliferation Database 0
Category members GO Category GO:0001945 lymph vessel development Database 0
Category members GO Category GO:0001946 lymphangiogenesis Database 0
Category members GO Category GO:0002088 lens development in camera-type eye Database 0
Category members GO Category GO:0003705 RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity Database 0
Category members GO Category GO:0003714 transcription corepressor activity Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0007420 brain development Database 0
Category members GO Category GO:0008284 positive regulation of cell proliferation Database 0
Category members GO Category GO:0010468 regulation of gene expression Database 0
Category members GO Category GO:0010595 positive regulation of endothelial cell migration Database 0
Category members GO Category GO:0021516 dorsal spinal cord development Database 0
Category members GO Category GO:0030240 skeletal muscle thin filament assembly Database 0
Category members GO Category GO:0031667 response to nutrient levels Database 0
Category members GO Category GO:0045071 negative regulation of viral genome replication Database 0
Category members GO Category GO:0045446 endothelial cell differentiation Database 0
Category members GO Category GO:0046619 optic placode formation involved in camera-type eye formation Database 0
Category members GO Category GO:0048839 inner ear development Database 0
Category members GO Category GO:0048845 venous blood vessel morphogenesis Database 0
Category members GO Category GO:0050693 LBD domain binding Database 0
Category members GO Category GO:0055009 atrial cardiac muscle tissue morphogenesis Database 0
Category members GO Category GO:0055010 ventricular cardiac muscle tissue morphogenesis Database 0
Category members GO Category GO:0060042 retina morphogenesis in camera-type eye Database 0
Category members GO Category GO:0060059 embryonic retina morphogenesis in camera-type eye Database 0
Category members GO Category GO:0060214 endocardium formation Database 0
Category members GO Category GO:0060298 positive regulation of sarcomere organization Database 0
Category members GO Category GO:0060412 ventricular septum morphogenesis Database 0
Category members GO Category GO:0060414 aorta smooth muscle tissue morphogenesis Database 0
Category members GO Category GO:0060421 positive regulation of heart growth Database 0
Category members GO Category GO:0060836 lymphatic endothelial cell differentiation Database 0
Category members GO Category GO:0060849 regulation of transcription involved in lymphatic endothelial cell fate commitment Database 0
Category members GO Category GO:0070309 lens fiber cell morphogenesis Database 0
Category members GO Category GO:0070858 negative regulation of bile acid biosynthetic process Database 0


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