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Query: PPEF2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PPEF2 0 1.425

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PPEF2 Phosphorylation Y466 1.425 _GGGCY(ph)FGPDVTQQLLQKYNMQFLIRS(ph)HECK_
PPEF2 Phosphorylation S487 1.425 _GGGCY(ph)FGPDVTQQLLQKYNMQFLIRS(ph)HECK_

Background Information for PPEF2:


Pubmed-PPEF2 »
Uniprot-PPEF2 »
Biogrid-PPEF2 »
ProteomicsDB-PPEF2 »

Tumorportal-PPEF2 »
COSMIC-PPEF2 »
GenomeRNAi-PPEF2 »
Genecards-PPEF2


Protein-protein Interactions for PPEF2
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in PPEF2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Ser/Thr-sp_prot-phosphatase IPR006186 0.88
Category members Calcineurin-like_PHP_apaH IPR004843 0.24
Category members Metallo-depent_PP-like IPR029052 0.23
Category members Ser/Thr-Pase_EF-hand_contain IPR012008 0.11
Category members EF_hand_dom IPR002048 0
Category members PPP_dom IPR013235 0


Protein complexes (CORUM database) featuring PPEF2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PPEF2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0043409 negative regulation of MAPK cascade Database 0.87
Category members GO Category GO:0043506 regulation of JUN kinase activity Database 0.35
Category members GO Category GO:0016787 hydrolase activity Database 0.22
Category members GO Category GO:0004722 protein serine/threonine phosphatase activity Database 0.11
Category members GO Category GO:0050906 detection of stimulus involved in sensory perception Database 0.11
Category members GO Category GO:0005509 calcium ion binding Database 0.11
Category members GO Category GO:0004721 phosphoprotein phosphatase activity Database 0.11
Category members GO Category GO:0030544 Hsp70 protein binding Database 0.1
Category members GO Category GO:0005506 iron ion binding Database 0.04
Category members GO Category GO:0001750 photoreceptor outer segment Database 0
Category members GO Category GO:0001917 photoreceptor inner segment Database 0
Category members GO Category GO:0006470 protein dephosphorylation Database 0
Category members GO Category GO:0007601 visual perception Database 0
Category members GO Category GO:0010801 negative regulation of peptidyl-threonine phosphorylation Database 0
Category members GO Category GO:0030145 manganese ion binding Database 0
Category members GO Category GO:0031435 mitogen-activated protein kinase kinase kinase binding Database 0
Category members GO Category GO:0043405 regulation of MAP kinase activity Database 0
Category members GO Category GO:0051879 Hsp90 protein binding Database 0


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