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Query: MTMR3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MTMR3 0 1.893 0.400 -0.600
MTMR3 0 1.893 0.510 -0.480

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MTMR3 Phosphorylation S633 0.471 0.821 _RCS(ph)DPSLNEK_
MTMR3 Phosphorylation T611 0.583 0.519 _T(ph)RSYDNLTTACDNTVPLASR_
MTMR3 Phosphorylation S647 -0.030 0.268 _S(ph)LELSSLAGPGEDPLSADSLGKPTR_
MTMR3 Phosphorylation S613 0.041 0.122 _S(ph)YDNLTTACDNTVPLASR_
MTMR3 Phosphorylation T731 -0.553 0.016 _RKT(ph)PEASAIGLHQDPELGDAALR_
MTMR3 Ubiquitylation K259 0.489 _NADDEHLVQSVAK(gl)ACASDSR_

Background Information for MTMR3:





Protein-protein Interactions for MTMR3

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ATM Cat. description Hein, Mann, Cell 2015
Category members IP bait THOC2 Cat. description Hein, Mann, Cell 2015
Category members IP bait ALOX5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait AURKA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DNAJC10 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HDAC11 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MED18 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PNO1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TULP3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MTMR3

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Znf_FYVE_PHD IPR011011 1.23
Category members Znf_FYVE IPR000306 0
Category members Tyr_Pase_cat IPR003595 0
Category members Myotubularin-like_Pase_dom IPR010569 0
Category members Znf_FYVE-rel IPR017455 0
Category members Prot-tyrosine_phosphatase-like IPR029021 0


Protein complexes (CORUM database) featuring MTMR3

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring MTMR3

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0046856 phosphatidylinositol dephosphorylation Database 0.35
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0004722 protein serine/threonine phosphatase activity Database 0.11
Category members GO Category GO:0006661 phosphatidylinositol biosynthetic process Database 0.06
Category members Pathway Pathway_103 REACTOME_PI_METABOLISM 0 0.04
Category members Pathway Pathway_100 REACTOME_PHOSPHOLIPID_METABOLISM 0 0
Category members Pathway Pathway_102 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE 0 0
Category members Pathway Pathway_4 REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 0 0
Category members GO Category GO:0004438 phosphatidylinositol-3-phosphatase activity Database 0
Category members GO Category GO:0004725 protein tyrosine phosphatase activity Database 0
Category members GO Category GO:0006470 protein dephosphorylation Database 0
Category members GO Category GO:0006644 phospholipid metabolic process Database 0
Category members GO Category GO:0016311 dephosphorylation Database 0
Category members GO Category GO:0016791 phosphatase activity Database 0
Category members GO Category GO:0035335 peptidyl-tyrosine dephosphorylation Database 0
Category members GO Category GO:0046872 metal ion binding Database 0


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