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Query: CDK5RAP3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CDK5RAP3 1 7.137 -1.460 2.740
CDK5RAP3 1 7.137 -1.460 2.740 0.784 1.125
CDK5RAP3 1 7.137 -1.460 2.740 0.905

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CDK5RAP3 Ubiquitylation K517 0.755 0.828 _LIEADISK(gl)R_
CDK5RAP3 Ubiquitylation K191 0.393 0.766 _EQFYHSCK(gl)QYGITGENVR_
CDK5RAP3 Ubiquitylation K503 -0.651 _LDLLLEK(gl)TK_
CDK5RAP3 Ubiquitylation K467 0.155 _LK(gl)QSQLLALKK_

Background Information for CDK5RAP3:


Pubmed-CDK5RAP3 »
Uniprot-CDK5RAP3 »
Biogrid-CDK5RAP3 »
ProteomicsDB-CDK5RAP3 »

Tumorportal-CDK5RAP3 »
COSMIC-CDK5RAP3 »
GenomeRNAi-CDK5RAP3 »
Genecards-CDK5RAP3


Protein-protein Interactions for CDK5RAP3
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait UFL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait AMTN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C19orf75 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CD274 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDK5RAP3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DDRGK1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRPS7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SRPRB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM206 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TPTE2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRIM44 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait UPF3A Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CDK5RAP3
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring CDK5RAP3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CDK5RAP3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0019901 protein kinase binding Database 0.37
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members GO Category GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity Database 0.13
Category members GO Category GO:0005575 cellular_component Database 0
Category members GO Category GO:0007420 brain development Database 0
Category members GO Category GO:0045664 regulation of neuron differentiation Database 0


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