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Query: CCNT1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CCNT1 0 2.789 0.720 -0.430 1.355 1.434

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for CCNT1:


Pubmed-CCNT1 »
Uniprot-CCNT1 »
Biogrid-CCNT1 »
ProteomicsDB-CCNT1 »

Tumorportal-CCNT1 »
COSMIC-CCNT1 »
GenomeRNAi-CCNT1 »
Genecards-CCNT1


Protein-protein Interactions for CCNT1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait AFF1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CTR9 Cat. description Hein, Mann, Cell 2015
Category members IP bait JUNB Cat. description Hein, Mann, Cell 2015
Category members IP bait MLLT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL35 Cat. description Hein, Mann, Cell 2015
Category members IP bait AFF4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CACNG2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDK6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDK9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait COMTD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CTSE Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ELL3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait H2AFY2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HEXIM1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HEXIM2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PIP4K2A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM150A Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CCNT1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Cyclin_N IPR006671 0
Category members Cyclin-like IPR013763 0


Protein complexes (CORUM database) featuring CCNT1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 2601 P-TEFb-BRD4-TRAP220 complex Database 1.23
Category members Corum 2599 POLR2A-CCNT1-CDK9-NCL-LEM6-CPSF2 complex Database 0.75
Category members Corum 2603 Transcription elongation factor complex (SUPT5H, CDK9, CCNT1) Database 0.7
Category members Corum 2875 BRD4-P-TEFb complex Database 0.7
Category members Corum 2877 BRD4-P-TEFb complex Database 0.7
Category members Corum 2600 BRD4 complex Database 0.63
Category members Corum 2639 HES1 promoter-Notch enhancer complex Database 0.45
Category members Corum 2604 P-TEFb-SKP2 complex Database 0.35
Category members Corum 2602 P-TEFb-7SKRNA-HEXIM1 complex Database 0.08
Category members Corum 2605 Heterotrimeric complex (CCNT1, CDK9, GRN) Database 0.08
Category members Corum 2873 P-TEFb-7SKRNA-HEXIM1 complex Database 0.08
Category members Corum 2878 P-TEFb-7SKRNA-HEXIM1 complex Database 0.08


Categories featuring CCNT1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0016032 viral process Database INF
Category members Pathway Pathway_197 REACTOME_HIV_INFECTION 0 12.07
Category members Pathway Pathway_196 REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS 0 9.67
Category members Pathway Pathway_376 REACTOME_HIV_LIFE_CYCLE 0 9.45
Category members Pathway Pathway_348 REACTOME_TRANSCRIPTION 0 9
Category members GO Category GO:0019048 modulation by virus of host morphology or physiology Database 7.81
Category members Pathway Pathway_374 REACTOME_LATE_PHASE_OF_HIV_LIFE_CYCLE 0 7.57
Category members GO Category GO:0003682 chromatin binding Database 6.07
Category members GO Category GO:0050434 positive regulation of viral transcription Database 4.8
Category members Pathway Pathway_360 REACTOME_FORMATION_OF_RNA_POL_II_ELONGATION_COMPLEX_ 0 3.35
Category members Pathway Pathway_375 REACTOME_RNA_POL_II_TRANSCRIPTION 0 2.46
Category members GO Category GO:0006368 transcription elongation from RNA polymerase II promoter Database 2.03
Category members Pathway Pathway_363 REACTOME_RNA_POL_II_PRE_TRANSCRIPTION_EVENTS 0 1.84
Category members Pathway Pathway_367 REACTOME_ELONGATION_ARREST_AND_RECOVERY 0 1.67
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0051301 cell division Database 1.15
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0006366 transcription from RNA polymerase II promoter Database 0.96
Category members GO Category GO:0017069 snRNA binding Database 0.96
Category members Pathway Pathway_777 REACTOME_SIGNALING_BY_TGF_BETA_RECEPTOR_COMPLEX 0 0.89
Category members GO Category GO:0007049 cell cycle Database 0.69
Category members GO Category GO:0019901 protein kinase binding Database 0.37
Category members GO Category GO:0006367 transcription initiation from RNA polymerase II promoter Database 0.25
Category members GO Category GO:0007179 transforming growth factor beta receptor signaling pathway Database 0.25
Category members Pathway Pathway_802 REACTOME_TRANSCRIPTIONAL_ACTIVITY_OF_SMAD2_SMAD3_SMAD4_HETEROTRIMER 0 0.17
Category members GO Category GO:0008024 positive transcription elongation factor complex b Database 0.16
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members GO Category GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity Database 0.13
Category members Pathway Pathway_822 REACTOME_GENERIC_TRANSCRIPTION_PATHWAY 0 0.09
Category members Pathway Pathway_808 REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION 0 0.08
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members GO Category GO:0044212 transcription regulatory region DNA binding Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0


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