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POLR2A-CCNT1-CDK9-NCL-LEM6-CPSF2 complex
(2599)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
NCL 3 -0.530 0.500 -0.279 -0.044 0.135
POLR2A 3 -0.397 0.863 1.593 -2.121 0.465
CDK9 2 -1.000 1.130 2.047 1.362 1.840 1.146 0.280
CCNT1 0 0.720 -0.430 1.355 1.434
CPSF2 0 0.150 0.340 -0.113 -0.032 0.570 0.441 0.355

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
CDK9 Ubiquitylation K35 -0.042 _IGQGTFGEVFK(gl)AR_
CDK9 Ubiquitylation K151 -0.345 _DMK(gl)AANVLITR_
CDK9 Ubiquitylation K178 -0.409 -1.058 _AFSLAK(gl)NSQPNR_
CDK9 Ubiquitylation K269 -1.874 _LELVK(gl)GQK_
CPSF2 Ubiquitylation K140 -0.692 _FSQIVNLKGK(gl)_
CPSF2 Ubiquitylation K324 -1.406 -1.082 _VPSPK(gl)VVLASQPDLECGFSR_
CPSF2 Ubiquitylation K725 0.157 _LSDFK(gl)QVLLR_
NCL Phosphorylation S67 0.084 0.215 _VVVS(ph)PTKK_
NCL Phosphorylation T69 0.262 0.250 _KVVVSPT(ph)KK_
NCL Ubiquitylation K70 0.073 _KVVVSPTK(gl)K_
NCL Ubiquitylation K71 0.073 _KVVVSPTK(gl)K_
NCL Phosphorylation T76 -0.311 -1.653 _KVAVAT(ph)PAK_
NCL Ubiquitylation K102 0.229 _TVTPAK(gl)AVTTPGKK_
NCL Ubiquitylation K116 0.184 _GATPGK(gl)ALVATPGKK_
NCL Phosphorylation T121 -0.434 -0.594 _ALVAT(ph)PGKK_
NCL Ubiquitylation K135 0.162 _GAAIPAKGAK(gl)_
NCL Ubiquitylation K324 1.129 _SAPELK(gl)TGISDVFAK_
NCL Ubiquitylation K333 1.065 _TGISDVFAK(gl)NDLAVVDVR_
NCL Ubiquitylation K377 0.914 _VFGNEIK(gl)LEKPK_
NCL Ubiquitylation K380 1.047 _VFGNEIKLEK(gl)PK_
NCL Ubiquitylation K398 0.982 1.070 _TLLAK(gl)NLPYK_
NCL Ubiquitylation K403 1.073 _NLPYK(gl)VTQDELK_
NCL Ubiquitylation K429 1.523 _SK(gl)GIAYIEFK_
NCL Ubiquitylation K467 1.082 _SISLYYTGEK(gl)GQNQDYR_
NCL Ubiquitylation K513 1.291 -0.285 _ATFIK(gl)VPQNQNGK_
NCL Phosphorylation S563 -0.006 0.046 _LELQGPRGS(ph)PNAR_
NCL Phosphorylation S580 1.509 0.943 _GLS(ph)EDTTEETLK_
NCL Ubiquitylation K589 0.843 _GLSEDTTEETLK(gl)ESFDGSVR_
NCL Phosphorylation S619 1.522 1.942 _GFGFVDFNS(ph)EEDAK_
POLR2A Ubiquitylation K32 1.006 _VQFGVLSPDELK(gl)R_
POLR2A Ubiquitylation K127 1.428 _IK(gl)DILAK_
POLR2A Ubiquitylation K132 0.487 _IKDILAK(gl)SK_
POLR2A Ubiquitylation K149 1.053 _LTHVYDLCK(gl)GK_
POLR2A Ubiquitylation K226 1.254 _VHEIFK(gl)R_
POLR2A Ubiquitylation K279 0.885 _NQDDLTHK(gl)LADIVK_
POLR2A Ubiquitylation K285 1.235 _LADIVK(gl)INNQLR_
POLR2A Ubiquitylation K417 0.662 _GNSQYPGAK(gl)YIIR_
POLR2A Ubiquitylation K707 1.333 _TYQDIQNTIK(gl)K_
POLR2A Ubiquitylation K710 1.362 1.417 _AK(gl)QDVIEVIEK_
POLR2A Ubiquitylation K751 -0.268 1.477 _DK(gl)TGSSAQK(gl)SLSEYNNFK_
POLR2A Ubiquitylation K758 -0.129 1.511 _DKTGSSAQK(gl)SLSEYNNFK_
POLR2A Ubiquitylation K767 1.702 _SLSEYNNFK(gl)SMVVSGAK_
POLR2A Ubiquitylation K775 1.252 _SMVVSGAK(gl)GSK_
POLR2A Ubiquitylation K812 -0.169 _TLPHFIK(gl)DDYGPESR_
POLR2A Ubiquitylation K976 0.145 0.332 _VIFPTGDSK(gl)VVLPCNLLR_
POLR2A Ubiquitylation K1014 0.766 _VVEGVK(gl)ELSK_
POLR2A Ubiquitylation K1125 4.356 1.173 _LK(gl)ELINISK_
POLR2A Ubiquitylation K1155 3.909 0.506 _AK(gl)DILCR_
POLR2A Ubiquitylation K1350 5.000 0.930 _VLSEK(gl)DVDPVR_
POLR2A Phosphorylation T1840 -1.940 _YT(ph)PTSPSYSPSSPEYTPTSPK_
POLR2A Phosphorylation T1842 -2.070 _YTPT(ph)SPSYS(ph)PSSPEYTPTSPK_
POLR2A Phosphorylation S1843 -1.841 -1.437 _YTPTS(ph)PSYSPSSPEYTPTSPK_
POLR2A Phosphorylation Y1846 -1.758 _YTPTSPSY(ph)SPSSPEYTPTS(ph)PK_
POLR2A Phosphorylation S1847 -1.016 -1.726 _Y(ph)TPTSPSYS(ph)PSSPEYTPT(ph)SPK_
POLR2A Phosphorylation S1849 -2.693 _YTPTSPSY(ph)SPS(ph)SPEYTPTSPK_
POLR2A Phosphorylation S1850 -1.360 -0.983 _YTPTSPSYSPSS(ph)PEYTPTS(ph)PK_
POLR2A Phosphorylation Y1853 -1.665 _YTPTSPSYSPSSPEY(ph)TPT(ph)SPK_
POLR2A Phosphorylation T1856 -1.740 _YTPTSPSYS(ph)PSSPEYTPT(ph)SPK_
POLR2A Phosphorylation S1857 -2.153 -2.282 _YTPTSPSYSPSSPEYTPTS(ph)PK_
POLR2A Phosphorylation T1877 -0.410 _YSPT(ph)SPTYS(ph)PTTPK_
POLR2A Phosphorylation S1878 -1.417 -0.623 _YSPTS(ph)PTYSPTT(ph)PK_
POLR2A Phosphorylation S1882 -0.491 0.086 _YSPTS(ph)PTYS(ph)PTTPK_
POLR2A Phosphorylation T1885 -0.372 -0.103 _YSPTS(ph)PTYSPTT(ph)PK_
POLR2A Phosphorylation S1889 -1.476 _YS(ph)PTSPTYSPTS(ph)PVYTPTSPK_
POLR2A Phosphorylation T1891 -3.041 -2.243 _YSPT(ph)SPTYSPTSPVYTPTSPK_
POLR2A Phosphorylation S1892 -2.675 -2.044 _YSPTS(ph)PTYSPTSPVYTPTSPK_
POLR2A Phosphorylation S1896 -1.174 _YSPTSPTYS(ph)PTSPVYTPT(ph)SPK_
POLR2A Phosphorylation T1898 -1.558 _YSPTS(ph)PTYSPT(ph)SPVYTPTSPK_
POLR2A Phosphorylation S1899 -0.903 -1.110 _YSPTSPTYSPTS(ph)PVYT(ph)PTSPK_
POLR2A Phosphorylation T1903 -0.180 -1.726 _YSPTSPTYSPTS(ph)PVYT(ph)PTSPK_
POLR2A Phosphorylation T1905 -1.328 -1.788 _YSPTSPTYSPTS(ph)PVYTPT(ph)SPK_
POLR2A Phosphorylation S1906 -2.720 -2.245 _YSPTS(ph)PTYSPTSPVYTPTS(ph)PK_
POLR2A Phosphorylation S1910 -1.108 -1.445 _YS(ph)PTSPTYS(ph)PTSPK_
POLR2A Phosphorylation T1912 -1.639 _YSPT(ph)SPTYS(ph)PTSPK_
POLR2A Phosphorylation S1913 -2.778 -1.508 _YSPTS(ph)PTYSPTS(ph)PK_
POLR2A Phosphorylation T1915 -2.612 _YSPTSPT(ph)YSPTSPK_
POLR2A Phosphorylation S1917 -2.286 -1.773 _YSPTS(ph)PTYS(ph)PTSPK_
POLR2A Phosphorylation T1919 -2.218 -1.471 _YSPTS(ph)PTYSPT(ph)SPK_
POLR2A Phosphorylation S1920 -1.088 -1.414 _YSPTS(ph)PTYSPTS(ph)PK_


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