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Query: CDK5RAP1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CDK5RAP1 0 -0.716 -0.230 0.000

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CDK5RAP1 Ubiquitylation K189 -0.716 _LK(gl)EEILNR_
CDK5RAP1 Ubiquitylation K348 -1.373 _GFTTNYKTK(gl)_
CDK5RAP1 Ubiquitylation K396 -1.590 _DNICK(gl)QIHLPAQSGSSR_
CDK5RAP1 Ubiquitylation K487 -1.858 _LK(gl)DDVPEEVK_
CDK5RAP1 Ubiquitylation K495 -1.951 _LKDDVPEEVK(gl)LR_

Background Information for CDK5RAP1:


Pubmed-CDK5RAP1 »
Uniprot-CDK5RAP1 »
Biogrid-CDK5RAP1 »
ProteomicsDB-CDK5RAP1 »

Tumorportal-CDK5RAP1 »
COSMIC-CDK5RAP1 »
GenomeRNAi-CDK5RAP1 »
Genecards-CDK5RAP1


Protein-protein Interactions for CDK5RAP1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait C9orf41 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDK5RAP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KIAA0930 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PDZK1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PLA2G10 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CDK5RAP1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members TRAM_dom IPR002792 0
Category members Methylthiotransferase IPR005839 0
Category members Elp3/MiaB/NifB IPR006638 0
Category members rSAM IPR007197 0
Category members Methylthiotransferase_N IPR013848 0


Protein complexes (CORUM database) featuring CDK5RAP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CDK5RAP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0032403 protein complex binding Database 0.49
Category members GO Category GO:0019901 protein kinase binding Database 0.37
Category members GO Category GO:0006400 tRNA modification Database 0.25
Category members GO Category GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity Database 0.13
Category members GO Category GO:0003824 catalytic activity Database 0.11
Category members GO Category GO:0016740 transferase activity Database 0.07
Category members GO Category GO:0005575 cellular_component Database 0
Category members GO Category GO:0007420 brain development Database 0
Category members GO Category GO:0009451 RNA modification Database 0
Category members GO Category GO:0043412 macromolecule modification Database 0
Category members GO Category GO:0045664 regulation of neuron differentiation Database 0
Category members GO Category GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity Database 0
Category members GO Category GO:0046872 metal ion binding Database 0
Category members GO Category GO:0051536 iron-sulfur cluster binding Database 0
Category members GO Category GO:0051539 4 iron, 4 sulfur cluster binding Database 0


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