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Query: BMPR1B

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
BMPR1B 0 1.933 -0.810 0.900

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
BMPR1B Ubiquitylation K477 1.033 _EIVCIK(gl)K_

Background Information for BMPR1B:


Pubmed-BMPR1B »
Uniprot-BMPR1B »
Biogrid-BMPR1B »
ProteomicsDB-BMPR1B »

Tumorportal-BMPR1B »
COSMIC-BMPR1B »
GenomeRNAi-BMPR1B »
Genecards-BMPR1B


Protein-protein Interactions for BMPR1B
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait C21orf63 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TPRA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in BMPR1B
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members TGFB_receptor IPR000333 0.1
Category members Kinase-like_dom IPR011009 0.03
Category members Activin_rcpt IPR000472 0
Category members Prot_kinase_dom IPR000719 0
Category members Ser-Thr/Tyr_kinase_cat_dom IPR001245 0
Category members Ser/Thr_dual-sp_kinase IPR002290 0
Category members TGF_beta_rcpt_GS IPR003605 0
Category members Tyr_kinase_cat_dom IPR020635 0


Protein complexes (CORUM database) featuring BMPR1B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring BMPR1B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members Pathway Pathway_448 KEGG_CYTOKINE_CYTOKINE_RECEPTOR_INTERACTION 0 2.05
Category members GO Category GO:0005887 integral to plasma membrane Database 1.69
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0004674 protein serine/threonine kinase activity Database 0.66
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0006954 inflammatory response Database 0.49
Category members GO Category GO:0045597 positive regulation of cell differentiation Database 0.45
Category members GO Category GO:0030509 BMP signaling pathway Database 0.2
Category members GO Category GO:0004672 protein kinase activity Database 0.19
Category members Pathway Pathway_893 KEGG_TGF_BETA_SIGNALING_PATHWAY 0 0.14
Category members GO Category GO:0002062 chondrocyte differentiation Database 0.13
Category members GO Category GO:0004702 receptor signaling protein serine/threonine kinase activity Database 0.1
Category members GO Category GO:0030154 cell differentiation Database 0.06
Category members GO Category GO:0043010 camera-type eye development Database 0.05
Category members GO Category GO:0043235 receptor complex Database 0.04
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members GO Category GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway Database 0.04
Category members Pathway Pathway_1211 REACTOME_SIGNALING_BY_BMP 0 0.04
Category members GO Category GO:0004713 protein tyrosine kinase activity Database 0.01
Category members Pathway Pathway_1133 PID_BMP_PATHWAY 0 0
Category members Disease phenotype Brachydactyly_type_A2 Brachydactyly type A2 Database 0
Category members GO Category GO:0001501 skeletal system development Database 0
Category members GO Category GO:0001502 cartilage condensation Database 0
Category members GO Category GO:0001550 ovarian cumulus expansion Database 0
Category members GO Category GO:0001654 eye development Database 0
Category members GO Category GO:0004675 transmembrane receptor protein serine/threonine kinase activity Database 0
Category members GO Category GO:0005024 transforming growth factor beta-activated receptor activity Database 0
Category members GO Category GO:0005025 transforming growth factor beta receptor activity, type I Database 0
Category members GO Category GO:0009953 dorsal/ventral pattern formation Database 0
Category members GO Category GO:0016772 transferase activity, transferring phosphorus-containing groups Database 0
Category members GO Category GO:0030501 positive regulation of bone mineralization Database 0
Category members GO Category GO:0031290 retinal ganglion cell axon guidance Database 0
Category members GO Category GO:0035108 limb morphogenesis Database 0
Category members GO Category GO:0042698 ovulation cycle Database 0
Category members GO Category GO:0045669 positive regulation of osteoblast differentiation Database 0
Category members GO Category GO:0046332 SMAD binding Database 0
Category members GO Category GO:0046872 metal ion binding Database 0
Category members GO Category GO:0060041 retina development in camera-type eye Database 0


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