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Query: ZFYVE16

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ZFYVE16 1 8.494 -1.080 1.970

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ZFYVE16 Ubiquitylation K1202 -2.966 3.670 _LGAEYK(gl)AYPAPLTSIR_
ZFYVE16 Phosphorylation S939 1.491 1.197 _NEIIQS(ph)PISQVPSVEK_
ZFYVE16 Ubiquitylation K1372 0.291 _ITCGK(gl)VDAVDLR_
ZFYVE16 Ubiquitylation K1257 0.166 0.179 _SCIK(gl)IPR_
ZFYVE16 Ubiquitylation K86 -0.638 _TLK(gl)GLTSIQNEK_
ZFYVE16 Ubiquitylation K455 -1.793 _K(gl)IDPDQTVIR_
ZFYVE16 Ubiquitylation K1364 -0.812 _LALREQK(gl)DFK_
ZFYVE16 Ubiquitylation K1367 -1.498 _DFK(gl)ITCGK_

Background Information for ZFYVE16:





Protein-protein Interactions for ZFYVE16

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait PTPN23 Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP1CA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PPP1CC Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ZFYVE16

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Znf_FYVE_PHD IPR011011 1.23
Category members Znf_FYVE_SARA/endofin IPR017165 0.05
Category members DUF3480 IPR022557 0.05
Category members Znf_FYVE IPR000306 0
Category members Znf_FYVE-rel IPR017455 0


Protein complexes (CORUM database) featuring ZFYVE16

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ZFYVE16

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005769 early endosome Database 1.26
Category members GO Category GO:0031901 early endosome membrane Database 0.58
Category members Pathway Pathway_933 PID_TGFBR_PATHWAY 0 0.52
Category members GO Category GO:0043231 intracellular membrane-bounded organelle Database 0.43
Category members GO Category GO:0016197 endosomal transport Database 0.43
Category members GO Category GO:0016050 vesicle organization Database 0.31
Category members GO Category GO:0008565 protein transporter activity Database 0.26
Category members GO Category GO:0030509 BMP signaling pathway Database 0.2
Category members Pathway Pathway_893 KEGG_TGF_BETA_SIGNALING_PATHWAY 0 0.14
Category members GO Category GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding Database 0.04
Category members Pathway Pathway_1211 REACTOME_SIGNALING_BY_BMP 0 0.04
Category members GO Category GO:0006622 protein targeting to lysosome Database 0.02
Category members Pathway Pathway_1133 PID_BMP_PATHWAY 0 0
Category members GO Category GO:0005545 1-phosphatidylinositol binding Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0030100 regulation of endocytosis Database 0
Category members GO Category GO:0046872 metal ion binding Database 0


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