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ST_JNK_MAPK_PATHWAY
(Pathway_21)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
JUN 3 -0.930 0.930 -0.126
ATF2 2 -1.380 1.800
MAPK9 1 0.110 -0.490
TAB1 1 1.890 -0.670
TAB1 1 1.890 -0.670 1.657
NR2C2 1 -2.470 4.780
TAB2 0 -0.030 -0.580
MAP2K4 0 -0.300 0.320
CDC42 0 -0.170 0.490 -0.597 -1.527 -1.013
CDC42 0 1.240 -0.940 -0.597 -1.527 -1.013
MAP2K7 0 0.180 -0.660 -2.110
MAP3K4 0 0.000 0.450
DLD 0 -0.420 0.270 1.380 0.780 -1.052 0.824 0.231
MAP3K1 0 0.750 -1.270
MYEF2 0 -0.766 -1.685 -0.392 -0.108 0.500
GAB1 0 1.950 -1.110
GADD45A 0 1.050 -0.170
MAP3K7 0 -1.120 1.140 -1.048
TP53 0 -1.070 1.050 -2.808 0.076 -0.094 0.436 0.497
AKT1 0 -0.050 0.700
AKT1 0 0.860 -0.040
MAP3K2 0 -1.220 1.960
MAP3K5 0 0.710 -0.770
MAP3K3 0 0.830 -0.050

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
AKT1 Phosphorylation S124 0.252 0.311 _SGS(ph)PSDNSGAEEMEVSLAKPK_
AKT1 Phosphorylation S126 -0.241 _SGSPS(ph)DNSGAEEM(ox)EVSLAK_
AKT1 Ubiquitylation K301 0.988 _EGIK(gl)DGATMK_
ATF2 Phosphorylation T71 -1.263 -1.166 _NDSVIVADQTPT(ph)PTR_
ATF2 Phosphorylation S90 2.624 2.389 _NCEEVGLFNELAS(ph)PFENEFKK_
ATF2 Phosphorylation S112 1.025 1.118 _MPLDLS(ph)PLATPIIR_
CDC42 Ubiquitylation K173 -1.839 _DDPSTIEK(gl)LAK_
CDC42 Ubiquitylation K178 -0.801 -0.716 _NK(gl)QKPITPETAEK_
CDC42 Ubiquitylation K180 -1.806 _QK(gl)PITPETAEK(gl)LAR_
CDC42 Ubiquitylation K189 -1.082 _QKPITPETAEK(gl)LAR_
CDC42 Ubiquitylation K198 0.550 1.159 _AVK(gl)YVECSALTQK_
CDC42 Ubiquitylation K208 -0.937 0.038 _YVECSALTQK(gl)GLK_
CDC42 Ubiquitylation K228 -2.488 _NVFDEAILAALEPPEPK(gl)K_
CDC42 Ubiquitylation K229 -1.254 _NVFDEAILAALEPPEPKK(gl)_
GAB1 Phosphorylation S266 0.756 0.551 _SYS(ph)HDVLPK_
GAB1 Phosphorylation S367 0.230 0.176 _TAS(ph)DTDSSYCIPTAGMS(ph)PSR_
GAB1 Phosphorylation T369 -0.352 _TASDT(ph)DSSYCIPTAGMS(ph)PSR_
GAB1 Phosphorylation S381 -0.481 0.139 _TASDTDSSYCIPTAGM(ox)S(ph)PSR_
GAB1 Phosphorylation S401 0.266 0.788 _DAS(ph)SQDCYDIPR_
GAB1 Phosphorylation S402 0.328 0.633 _DASS(ph)QDCYDIPR_
GAB1 Phosphorylation S419 0.540 _SSS(ph)LEGFHNHFK_
GADD45A Ubiquitylation K12 -0.515 0.281 _TLEEFSAGEQK(gl)TER_
GADD45A Ubiquitylation K29 0.092 _VGDALEEVLSK(gl)ALSQR_
JUN Phosphorylation S58 -0.167 -1.247 _AKNS(ph)DLLTSPDVGLLK_
JUN Phosphorylation T62 2.545 1.674 _NSDLLT(ph)SPDVGLLK_
JUN Phosphorylation S63 2.030 1.458 _NSDLLTS(ph)PDVGLLK_
JUN Ubiquitylation K70 9.213 _NSDLLTSPDVGLLK(gl)_
JUN Phosphorylation S73 1.499 0.845 _LAS(ph)PELER_
JUN Phosphorylation S243 -0.642 -1.399 _LQALKEEPQTVPEMPGETPPLS(ph)PIDMESQER_
JUN Ubiquitylation K309 1.034 0.155 _EQVAQLK(gl)QK_
MAP2K4 Phosphorylation S80 0.441 _LRTHS(ph)IESSGK_
MAP2K7 Ubiquitylation K9 -1.406 _(ac)AASSLEQK(gl)LSR_
MAP2K7 Ubiquitylation K300 -1.228 _GQIK(gl)LCDFGISGR_
MAP2K7 Ubiquitylation K442 -1.326 _DVMAK(gl)TESPR_
MAP3K1 Phosphorylation S292 0.209 _RAPS(ph)PDGFSPYSPEETNR_
MAP3K1 Phosphorylation S506 1.427 _SHDFYSHELS(ph)SPVDSPSSLR_
MAP3K1 Phosphorylation S507 1.436 _SHDFYSHELSS(ph)PVDSPSSLR_
MAP3K1 Phosphorylation S923 0.127 -0.120 _LSAS(ph)SEDISER_
MAP3K2 Phosphorylation S153 0.506 -0.231 _RLS(ph)IIGPTSR_
MAP3K2 Phosphorylation S163 -0.910 -0.776 _DRS(ph)SPPPGYIPDELHQVAR_
MAP3K2 Phosphorylation S164 -0.743 -0.966 _DRS(ph)SPPPGYIPDELHQVAR_
MAP3K2 Phosphorylation S239 -0.284 -0.618 _AQS(ph)YPDNHQEFSDYDNPIFEK_
MAP3K2 Phosphorylation S331 0.008 _RRGS(ph)DIDNPTLTVM(ox)DISPPSR_
MAP3K3 Phosphorylation S166 -0.325 _HLS(ph)VSSQNPGR_
MAP3K3 Phosphorylation S175 0.120 -0.091 _S(ph)SPPPGYVPER_
MAP3K3 Phosphorylation S176 0.120 -0.091 _S(ph)SPPPGYVPER_
MAP3K3 Phosphorylation S250 -0.070 _AQS(ph)FPDNR_
MAP3K4 Ubiquitylation K406 0.367 _DLNQK(gl)LR_
MAP3K4 Phosphorylation S1252 -0.654 _HSS(ph)PTEERDEPAYPR_
MAP3K5 Phosphorylation S1066 -1.241 _SISLPVPVLVEDTSSSSEYGSVS(ph)PDTELKVDPFSFK_
MAP3K5 Phosphorylation S1113 -1.408 -0.562 _TLFLGIPDENFEDHSAPPS(ph)PEEK_
MAP3K7 Phosphorylation S374 0.149 -0.337 _GS(ph)SVESLPPTSEGK_
MAP3K7 Phosphorylation S375 0.171 -0.087 _GSS(ph)VESLPPTSEGK_
MAP3K7 Phosphorylation S389 1.072 1.445 _RMS(ph)ADMSEIEAR_
MAP3K7 Phosphorylation S439 0.246 0.198 _S(ph)IQDLTVTGTEPGQVSSR_
MAP3K7 Ubiquitylation K474 -0.385 -0.242 _MITTSGPTSEK(gl)PTR_
MAP3K7 Ubiquitylation K589 -0.104 _SLSTYYQQCK(gl)K_
MAP3K7 Ubiquitylation K590 -0.551 0.560 _K(gl)QLEVIR_
MAPK9 Phosphorylation Y185 3.533 _TACTNFMMTPY(ph)VVTR_
MYEF2 Phosphorylation T13 -1.184 -1.261 _(ac)ADANKAEVPGAT(ph)GGDSPHLQPAEPPGEPR_
MYEF2 Phosphorylation S17 -1.239 -1.089 _AEVPGATGGDS(ph)PHLQPAEPPGEPR_
MYEF2 Ubiquitylation K117 0.042 _WQAIK(gl)DLMR_
MYEF2 Ubiquitylation K521 0.604 _IGSK(gl)GNQIFVR_
NR2C2 Ubiquitylation K250 -0.596 _SPLIATPTFVADK(gl)DGAR_
NR2C2 Phosphorylation S370 -0.170 _DQS(ph)TPIIEVEGPLLSDTHVTFK_
NR2C2 Phosphorylation T371 0.442 -0.117 _DQST(ph)PIIEVEGPLLSDTHVTFK_
TAB1 Phosphorylation S7 -0.170 0.140 _S(ph)LLQSEQQPSWTDDLPLCHLSGVGSASNR_
TAB1 Phosphorylation S16 -0.138 0.069 _SLLQSEQQPS(ph)WTDDLPLCHLSGVGSASNR_
TAB1 Ubiquitylation K186 -1.015 _SYSADGK(gl)GTESHPPEDSWLK_
TAB1 Ubiquitylation K371 0.032 _LSQLGLDAGK(gl)IK_
TAB1 Ubiquitylation K373 -0.007 _LSQLGLDAGKIK(gl)_
TAB2 Phosphorylation S580 -0.075 _S(ph)NSISQIPSLEEMQQLR_
TAB2 Phosphorylation S582 0.331 _SNS(ph)ISQIPSLEEMQQLR_
TAB2 Ubiquitylation K653 -0.519 -0.200 _SIIK(gl)TPK_
TP53 Ubiquitylation K120 -0.188 _LGFLHSGTAK(gl)SVTCTYSPALNK_
TP53 Ubiquitylation K164 0.157 -1.260 _AMAIYK(gl)QSQHMTEVVR_
TP53 Phosphorylation S314 -0.695 -1.000 _ALPNNTSS(ph)SPQPK_
TP53 Phosphorylation S315 -0.762 -0.959 _RALPNNTSSS(ph)PQPK_
TP53 Ubiquitylation K320 -0.978 _ALPNNTSSSPQPKK(gl)_
TP53 Ubiquitylation K357 -0.231 -0.823 _ELNEALELKDAQAGK(gl)EPGGSR_


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