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Query: ADORA2B

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ADORA2B 0 0.405 -0.080 0.070

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ADORA2B Ubiquitylation K303 0.335 _YTFHK(gl)IISR_

Background Information for ADORA2B:


Pubmed-ADORA2B »
Uniprot-ADORA2B »
Biogrid-ADORA2B »
ProteomicsDB-ADORA2B »

Tumorportal-ADORA2B »
COSMIC-ADORA2B »
GenomeRNAi-ADORA2B »
Genecards-ADORA2B


Protein-protein Interactions for ADORA2B
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in ADORA2B
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members GPCR_Rhodpsn IPR000276 2.56
Category members GPCR_Rhodpsn_7TM IPR017452 2.32
Category members 7TM_GPCR_olfarory/Srsx IPR019424 0.46
Category members Adenosn_rcpt IPR001634 0


Protein complexes (CORUM database) featuring ADORA2B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ADORA2B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members Pathway Pathway_1105 REACTOME_GPCR_LIGAND_BINDING 0 2.35
Category members GO Category GO:0004930 G-protein coupled receptor activity Database 2.1
Category members Pathway Pathway_1184 KEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION 0 1.89
Category members Pathway Pathway_1182 REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS 0 1.69
Category members GO Category GO:0005887 integral to plasma membrane Database 1.69
Category members GO Category GO:0007186 G-protein coupled receptor signaling pathway Database 1.53
Category members Pathway Pathway_243 REACTOME_GPCR_DOWNSTREAM_SIGNALING 0 1.27
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members Pathway Pathway_256 REACTOME_SIGNALING_BY_GPCR 0 0.83
Category members Pathway Pathway_253 REACTOME_G_ALPHA_S_SIGNALLING_EVENTS 0 0.26
Category members Pathway Pathway_210 PID_CMYB_PATHWAY 0 0.2
Category members Pathway Pathway_233 KEGG_CALCIUM_SIGNALING_PATHWAY 0 0.13
Category members GO Category GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway Database 0.11
Category members GO Category GO:0007588 excretion Database 0.08
Category members GO Category GO:0030819 positive regulation of cAMP biosynthetic process Database 0.04
Category members GO Category GO:0032755 positive regulation of interleukin-6 production Database 0.04
Category members Pathway Pathway_160 KEGG_VASCULAR_SMOOTH_MUSCLE_CONTRACTION 0 0.01
Category members Pathway Pathway_1183 REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS 0 0
Category members GO Category GO:0000187 activation of MAPK activity Database 0
Category members GO Category GO:0001609 G-protein coupled adenosine receptor activity Database 0
Category members GO Category GO:0006968 cellular defense response Database 0
Category members GO Category GO:0007190 activation of adenylate cyclase activity Database 0
Category members GO Category GO:0007254 JNK cascade Database 0
Category members GO Category GO:0010575 positive regulation vascular endothelial growth factor production Database 0
Category members GO Category GO:0030828 positive regulation of cGMP biosynthetic process Database 0
Category members GO Category GO:0031284 positive regulation of guanylate cyclase activity Database 0
Category members GO Category GO:0031668 cellular response to extracellular stimulus Database 0
Category members GO Category GO:0032722 positive regulation of chemokine production Database 0
Category members GO Category GO:0043306 positive regulation of mast cell degranulation Database 0
Category members GO Category GO:0060087 relaxation of vascular smooth muscle Database 0


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