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Query: MADD

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MADD 0 1.072 0.620 -1.050

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MADD Phosphorylation T1061 0.390 0.682 _KRS(ph)PTESVNTPVGK_
MADD Phosphorylation S1059 0.390 0.618 _KRS(ph)PTESVNTPVGK_
MADD Phosphorylation S1239 0.070 -0.211 _GTLS(ph)DSEIETNSATSTIFGK_
MADD Phosphorylation T1237 -0.523 -0.591 _GT(ph)LSDSEIETNSATSTIFGK_

Background Information for MADD:


Pubmed-MADD »
Uniprot-MADD »
Biogrid-MADD »
ProteomicsDB-MADD »

Tumorportal-MADD »
COSMIC-MADD »
GenomeRNAi-MADD »
Genecards-MADD


Protein-protein Interactions for MADD
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ALOX5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BBS7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DOCK5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NXPH2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRMT6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNX21 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SYT12 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SYT3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SYT6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TSPYL6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MADD
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members DENN_dom IPR001194 0
Category members dDENN_dom IPR005112 0
Category members uDENN_dom IPR005113 0


Protein complexes (CORUM database) featuring MADD
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring MADD
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0042981 regulation of apoptotic process Database 0.79
Category members Pathway Pathway_963 BIOCARTA_TNFR1_PATHWAY 0 0.44
Category members Pathway Pathway_961 PID_CASPASE_PATHWAY 0 0.19
Category members GO Category GO:0051726 regulation of cell cycle Database 0.11
Category members GO Category GO:0007166 cell surface receptor signaling pathway Database 0.1
Category members Pathway Pathway_734 PID_CERAMIDE_PATHWAY 0 0
Category members Pathway Pathway_738 PID_TNF_PATHWAY 0 0
Category members GO Category GO:0000187 activation of MAPK activity Database 0
Category members GO Category GO:0005123 death receptor binding Database 0
Category members GO Category GO:0017112 Rab guanyl-nucleotide exchange factor activity Database 0
Category members GO Category GO:0030295 protein kinase activator activity Database 0
Category members GO Category GO:0032483 regulation of Rab protein signal transduction Database 0


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