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Query: SNX1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SNX1 0 1.343 -0.090 -0.590

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SNX1 Ubiquitylation K179 1.013 0.331 _SK(gl)QFAVK_
SNX1 Ubiquitylation K223 -0.206 _SLIGMTKVK(gl)_

Background Information for SNX1:


Pubmed-SNX1 »
Uniprot-SNX1 »
Biogrid-SNX1 »
ProteomicsDB-SNX1 »

Tumorportal-SNX1 »
COSMIC-SNX1 »
GenomeRNAi-SNX1 »
Genecards-SNX1


Protein-protein Interactions for SNX1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait C1orf87 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCDC102B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCNL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DNM3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM90A1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FXR2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GPX7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HCLS1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KLHL10 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MLX Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait POTEB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNX1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNX32 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STAM Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMOD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF397 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SNX1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Phox IPR001683 0.24
Category members Vps5_C IPR015404 0.08
Category members Sorting_nexin_N IPR005329 0


Protein complexes (CORUM database) featuring SNX1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1091 SNX complex (SNX1a, SNX2, SNX4, LEPR) Database 0.05
Category members Corum 1093 SNX complex (SNX1a, SNX2, SNX4, INSR) Database 0.05
Category members Corum 1095 SNX complex (SNX1a, SNX2, SNX4, EGFR) Database 0.05
Category members Corum 1096 SNX complex (SNX1,1a,2,4, PDGF receptor) Database 0.05
Category members Corum 1058 SNX complex (SNX1, SNX6) Database 0
Category members Corum 1059 Retromer complex (SNX1, SNX2, VPS35, VPS29, VPS26A) Database 0
Category members Corum 1060 Retromer complex (SNX1, SNX2, VPS35, VPS29, VPS26B) Database 0
Category members Corum 1070 SNX complex (SNX1a, SNX2, SNX4) Database 0
Category members Corum 1104 SNX complex (SNX1a, SNX2, SNX4, TFRC) Database 0
Category members Corum 657 Retromer complex (SNX1, SNX2, VPS35, VPS29, VPS26A) Database 0


Categories featuring SNX1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0006886 intracellular protein transport Database 2.48
Category members GO Category GO:0035091 phosphatidylinositol binding Database 0.62
Category members GO Category GO:0031901 early endosome membrane Database 0.58
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0043231 intracellular membrane-bounded organelle Database 0.43
Category members GO Category GO:0016197 endosomal transport Database 0.43
Category members GO Category GO:0006897 endocytosis Database 0.31
Category members GO Category GO:0005768 endosome Database 0.29
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members GO Category GO:0008565 protein transporter activity Database 0.26
Category members Pathway Pathway_428 PID_THROMBIN_PAR1_PATHWAY 0 0.18
Category members Pathway Pathway_294 PID_AJDISS_2PATHWAY 0 0.18
Category members GO Category GO:0007154 cell communication Database 0
Category members GO Category GO:0010008 endosome membrane Database 0
Category members GO Category GO:0034498 early endosome to Golgi transport Database 0
Category members GO Category GO:0045732 positive regulation of protein catabolic process Database 0


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