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Query: DACH1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
DACH1 0 -0.646

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
DACH1 Ubiquitylation K713 -0.067 -0.579 _EQAEQTLK(gl)QAASTDSLR_

Background Information for DACH1:


Pubmed-DACH1 »
Uniprot-DACH1 »
Biogrid-DACH1 »
ProteomicsDB-DACH1 »

Tumorportal-DACH1 »
COSMIC-DACH1 »
GenomeRNAi-DACH1 »
Genecards-DACH1


Protein-protein Interactions for DACH1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait DACH1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DACH2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GPSM1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NCKIPSD Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SCOC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRIM44 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WDR83 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in DACH1
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring DACH1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring DACH1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0030336 negative regulation of cell migration Database 0.85
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members GO Category GO:0010944 negative regulation of transcription by competitive promoter binding Database 0.59
Category members GO Category GO:0005667 transcription factor complex Database 0.19
Category members GO Category GO:0007585 respiratory gaseous exchange Database 0.08
Category members GO Category GO:0008283 cell proliferation Database 0.06
Category members GO Category GO:0001967 suckling behavior Database 0.05
Category members GO Category GO:0001078 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription Database 0.04
Category members GO Category GO:0000122 negative regulation of transcription from RNA polymerase II promoter Database 0.02
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0046545 development of primary female sexual characteristics Database 0
Category members GO Category GO:0048147 negative regulation of fibroblast proliferation Database 0
Category members GO Category GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly Database 0
Category members GO Category GO:0060244 negative regulation of cell proliferation involved in contact inhibition Database 0


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