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Query: ROR2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ROR2 0 0.880 0.180 -0.350

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ROR2 Ubiquitylation K97 0.598 _WLK(gl)NDAPVVQEPR_
ROR2 Ubiquitylation K510 -0.960 _TLK(gl)DKAEGPLREEFR_
ROR2 Ubiquitylation K512 0.282 _DK(gl)AEGPLREEFR_

Background Information for ROR2:


Pubmed-ROR2 »
Uniprot-ROR2 »
Biogrid-ROR2 »
ProteomicsDB-ROR2 »

Tumorportal-ROR2 »
COSMIC-ROR2 »
GenomeRNAi-ROR2 »
Genecards-ROR2


Protein-protein Interactions for ROR2
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in ROR2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Ig-like_dom IPR007110 0.6
Category members Ig_sub IPR003599 0.43
Category members Immunoglobulin IPR013151 0.23
Category members Ig_sub2 IPR003598 0.21
Category members Ig_I-set IPR013098 0.13
Category members Ig_V-set IPR013106 0.09
Category members Kinase-like_dom IPR011009 0.03
Category members Kringle IPR000001 0
Category members Prot_kinase_dom IPR000719 0
Category members Ser-Thr/Tyr_kinase_cat_dom IPR001245 0
Category members Ser/Thr_dual-sp_kinase IPR002290 0
Category members Kringle-like IPR013806 0
Category members Tyr_kinase_rcpt_ROR IPR016247 0
Category members Frizzled_dom IPR020067 0
Category members Tyr_kinase_cat_dom IPR020635 0


Protein complexes (CORUM database) featuring ROR2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ROR2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0005887 integral to plasma membrane Database 1.69
Category members GO Category GO:0007275 multicellular organismal development Database 0.31
Category members GO Category GO:0008285 negative regulation of cell proliferation Database 0.28
Category members GO Category GO:0045893 positive regulation of transcription, DNA-dependent Database 0.28
Category members GO Category GO:0004672 protein kinase activity Database 0.19
Category members Pathway Pathway_417 PID_WNT_NONCANONICAL_PATHWAY 0 0.09
Category members GO Category GO:0030154 cell differentiation Database 0.06
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members GO Category GO:0017147 Wnt-protein binding Database 0.02
Category members GO Category GO:0060071 Wnt signaling pathway, planar cell polarity pathway Database 0.02
Category members GO Category GO:0004713 protein tyrosine kinase activity Database 0.01
Category members Pathway Pathway_1277 PID_WNT_SIGNALING_PATHWAY 0 0
Category members Disease phenotype ROBINOW_SYNDROME_AUTOSOMAL_DOMINANT ROBINOW SYNDROME AUTOSOMAL DOMINANT Database 0
Category members GO Category GO:0001501 skeletal system development Database 0
Category members GO Category GO:0001502 cartilage condensation Database 0
Category members GO Category GO:0001756 somitogenesis Database 0
Category members GO Category GO:0004714 transmembrane receptor protein tyrosine kinase activity Database 0
Category members GO Category GO:0005109 frizzled binding Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway Database 0
Category members GO Category GO:0007223 Wnt signaling pathway, calcium modulating pathway Database 0
Category members GO Category GO:0007254 JNK cascade Database 0
Category members GO Category GO:0016772 transferase activity, transferring phosphorus-containing groups Database 0
Category members GO Category GO:0030335 positive regulation of cell migration Database 0
Category members GO Category GO:0030538 embryonic genitalia morphogenesis Database 0
Category members GO Category GO:0042472 inner ear morphogenesis Database 0


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