bioLOGIC Category
Results for the Category
Wnt signaling pathway, planar cell polarity pathway
(GO:0060071)
RNAi screen result
|
RNAPII IP (MG132) |
CSB IP |
CSB IP (MG132) |
Chrom. |
Chrom. (MG132) |
Ubi /Phospo |
Ubi /Phospho (MG132) |
W |
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Gene name |
MGoogle Score |
RNAi high |
RNAi low |
RNAPII-IP (MG132) |
CSB-IP |
CSB-IP (MG132) |
Chrom. |
Chrom. (MG132) |
DVL2
|
0
|
-0.050
|
0.580
|
|
|
|
|
|
WNT5A
|
0
|
|
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|
|
|
|
RAC1
|
0
|
-0.580
|
1.580
|
0.486
|
|
|
-0.364
|
-0.568
|
DVL3
|
0
|
0.890
|
-0.290
|
|
|
|
|
|
VANGL2
|
0
|
-1.030
|
1.450
|
|
|
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|
|
ROR2
|
0
|
0.180
|
-0.350
|
|
|
|
|
|
MED12
|
0
|
-0.180
|
-0.500
|
|
|
|
-1.501
|
-0.491
|
Gene name |
PTM type |
PTM site |
UV |
UV (MG132) |
Sequence |
DVL2
|
Ubiquitylation
|
K343
|
0.846
|
-1.366
|
_DIVHK(gl)PGPIVLTVAK_
|
DVL3
|
Phosphorylation
|
S112
|
-0.787
|
|
_TGGIGDS(ph)RPPSFHPHAGGGSQENLDNDTETDSLVSAQR_
|
DVL3
|
Phosphorylation
|
S125
|
-0.854
|
-0.531
|
_TGGIGDSRPPSFHPHAGGGS(ph)QENLDNDTETDSLVSAQR_
|
MED12
|
Ubiquitylation
|
K429
|
|
-0.439
|
_EIEQQIK(gl)ER_
|
MED12
|
Ubiquitylation
|
K531
|
|
-0.272
|
_AMVVAKLLEK(gl)_
|
MED12
|
Phosphorylation
|
S635
|
-1.278
|
-0.801
|
_GDLAFGAPGPRPPS(ph)PFDDPADDPEHK_
|
MED12
|
Ubiquitylation
|
K1001
|
|
-1.092
|
_VK(gl)NTIYCNVEPSESNMR_
|
MED12
|
Ubiquitylation
|
K1661
|
|
-1.781
|
_DVITCEPQGSLIDTK(gl)GNK_
|
MED12
|
Ubiquitylation
|
K1682
|
|
-0.745
|
_EGLQVSTK(gl)QK_
|
MED12
|
Ubiquitylation
|
K1684
|
|
-0.960
|
_EGLQVSTK(gl)QK_
|
RAC1
|
Ubiquitylation
|
K115
|
-1.745
|
-0.215
|
_AK(gl)WYPEVR_
|
RAC1
|
Ubiquitylation
|
K142
|
0.492
|
|
_LDLRDDK(gl)DTIEK_
|
RAC1
|
Ubiquitylation
|
K152
|
0.099
|
-0.292
|
_K(gl)LTPITYPQGLAMAK_
|
RAC1
|
Ubiquitylation
|
K166
|
-0.981
|
-0.655
|
_LTPITYPQGLAMAK(gl)EIGAVK_
|
RAC1
|
Ubiquitylation
|
K172
|
1.026
|
0.412
|
_EIGAVK(gl)YLECSALTQR_
|
RAC1
|
Ubiquitylation
|
K185
|
-0.113
|
0.578
|
_GLK(gl)TVFDEAIR_
|
RAC1
|
Ubiquitylation
|
K202
|
-1.379
|
-1.447
|
_AVLCPPPVK(gl)KR_
|
RAC1
|
Ubiquitylation
|
K203
|
-1.708
|
-1.447
|
_AVLCPPPVKK(gl)_
|
ROR2
|
Ubiquitylation
|
K97
|
|
0.598
|
_WLK(gl)NDAPVVQEPR_
|
ROR2
|
Ubiquitylation
|
K510
|
-0.960
|
|
_TLK(gl)DKAEGPLREEFR_
|
ROR2
|
Ubiquitylation
|
K512
|
0.282
|
|
_DK(gl)AEGPLREEFR_
|
VANGL2
|
Ubiquitylation
|
K379
|
0.582
|
|
_LQEEEQK(gl)NPR_
|
WNT5A
|
Ubiquitylation
|
K268
|
|
-0.304
|
_VGDALK(gl)EK_
|
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